抗生素临床合理应用的药学干预方法研究

Study on Pharmaceutical Intervention in the Reasonable Application of Antibiotics

目的:研究药学干预在抗生素临床合理应用中的作用,为推进抗生素合理应用提供新思路。方法:随机选取2014年1年我院收治的400例患者,随机分为两组,每组各200例,对照组予以常规抗生素管理,观察组采用药学干预促进抗生素的合理应用,记录比较两组临床治疗效果、抗生素使用情况及费用。结果:观察组治疗有效率高于对照组,P<0.05;观察组抗生素使用率、不合理使用率、抗生素费用及抗生素耗费占总医疗费用比均低于对照组,比较差异均有统计学意义(P<0.05)。结论:药学干预可提高患者治疗效果,减少抗生素使用及不合理应用,可减轻患者经济负担,对促进抗生素临床合理应用具有重要意义。

Objective: To study the effect of pharmaceutical intervention in the reasonable application of antibiotics and to provide new ideas for the reasonable application of antibiotics.Methods:400 patients in our hospital from January to December 2014 were selected and randomly divided into the observation group and the control group,each group contained 200 patients. The control group was given conventional antibiotics administration,while the observation group was given pharmaceutical intervention.The curative effects,the situation of using of antibiotic and the cost of antibiotics were recorded and compared between the two groups.Results:In the observation group,the effective rate of observation group was higher than that of control group(P<0.05).Observation group of antibiotics use rate,unreasonable use rate and cost of antibiotics and antibiotic consumption accounted for total health care costs are lower than the control group,the differences were statistically significant (P<0.05). Conclusion:Pharmaceutical intervention can improve patients’ curative effects,reduce the utilization and Unreasonable utilization of antibiotics and reduce the economic burden of patients.It has an important significance in promoting the resonable application of antibiotics.