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声触诊组织成像量化技术鉴别诊断甲状腺TI—RADS4类结节的临床研究 被引量:11

Virtual touch tissue imaging quantification in differential diagnosis of benign and malignant TI-RADS 4 thyroid nodules
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摘要 目的探讨声触诊组织成像量化(VTIQ)技术在甲状腺影像报告及数据系统(TI—RADs)4类结节鉴别诊断中的应用价值。方法将185例患者共192个TI—RADS4类结节按最大径分为三组:Ⅱ组,最大径≤0.6cm;Ⅱ组,0.6cm%最大径≤1.0cm;Ⅲ组,最大径〉1.0cm。应用VTIQ技术测量三组结节剪切波速度(SWV)并比较其大小差异,以病理结果为金标准,利用ROC曲线寻找最佳诊断界值并评价其诊断效能。结果经ROC曲线检验,Ⅱ、Ⅱ、Ⅲ组以SwV值2.44m/s、2.44m/s、2.49m/s作为诊断界值其鉴别良恶性的敏感性分别为79.0%、76.0%、88.6%,特异性分别为88.6%、89.5%、93.7%,准确性分别为83.5%、81.8%、90.1%,约登指数分别为0.68、0.66、0.82。结论VTIQ能较好地反映TI—RADS4类结节的硬度,对此类结节的鉴别诊断价值较高,不受结节大小限制,方便且无创。 Objective To observe the value of virtual tough tissue imaging quantification (VTIQ) in differential diagnosis of thyroid imaging reporting and data system(TI-RADS) 4 thyroid nodules. Methods A total of 185 patients with 192 TI-RADS 4 nodules were included in this study. The nodules were divided into three groups according to the maximum size as follows:Group Ⅰ , the maximum size≤0.6 cm;Group Ⅱ , 0.6 cm〈 the maximum size≤ 1.0 cm ; Group Ⅲ , the maximum size 〉 1.0 cm. Shear wave velocities (SWV) of nodules were measured by means of VTIQ technique. With pathological diagnosis as the gold standard, SWV value of benign and malignant nodules were analyzed and ROC curve was drawn to assess the diagnostic efficiency. Results By the ROC curve test, at SWV cut-off values of 2.44 m/s for group Ⅰ and group Ⅱ,2.49 m/s for group Ⅲ ,the sensitivity were 79.0%,76.0%,88.6%,specificity were88.6%, 89.5%,93.7%,accuracy were 83.5%, 81.8%,90.1%, Youden index were 0.68,0.66,0.82, respectively. Conclusions VTIQ can reflect the hardness of TI-RADS 4 nodules, the value of the differential diagnosis of such nodules is high, convenient, noninvasive and not limited by the size of nodules.
出处 《中华超声影像学杂志》 CSCD 北大核心 2016年第7期573-578,共6页 Chinese Journal of Ultrasonography
基金 浙江省自然科学基金项目(LY16H180004)
关键词 弹性成像技术 甲状腺结节 甲状腺影像报告及数据系统 声触诊组织成像量化技术 Elasticity imaging techniques Thyroid nodule TI-RADS Virtual tough tissue imaging quantification
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