1,6-二磷酸果糖治疗小儿病毒性心肌炎的效果及对心肌酶谱的影响

Effect of 1,6-diphosphate in the treatment of children patient with viral myocarditis and its influence on myocardial enzyme spectrum

目的探讨1,6-二磷酸果糖治疗小儿病毒性心肌炎(VM)的效果及对心肌酶谱的影响。方法选取2014年1月～2015年6月在本院接受治疗的30例VM患儿作为研究对象,随机分为观察组及对照组,各15例。对照组采用常规治疗,观察组在对照组的基础上给予1,6-二磷酸果糖,比较两组的治疗效果、心电图及心肌酶谱改善情况。结果观察组的治疗总有效率为93.33%,显著高于对照组的73.33%,差异有统计学意义(P<0.05)。观察组心电图恢复正常患儿所占比例为80.00%,显著高于对照组的53.33%,差异有统计学意义(P<0.05)。观察组治疗后的心肌酶水平显著低于对照组治疗后,差异有统计学意义(P<0.05)。结论 1,6-二磷酸果糖可有效提高小儿VM的治疗效果,显著改善患儿的心电图及心肌酶谱,值得临床推广应用。

Objective To explore the effect of 1,6-diphosphate(FDP) in the treatment of children with viral myocarditis and its influence on myocardial enzyme spectrum. Methods 30 children patients with myocardial enzymes(VM) in our hospital from January 2014 to June 2015 were selected and randomly divided into the observation group and the control group,15 cases in each group.The control group was given conventional treatment,the observation group was treated with FDP on the basis of the control group.The treatment effect,the improvement condition of electrocardiogram and myocardial enzyme spectrum in the two groups was compared. Results The totally effective rate of the observation group was 93.33%,which was higher than 73.33% of the control group,with significant difference(P<0.05).The proportion of childrens whose electrocardiogram returned to normal in the observation group was 80.00%,which was higher than 53.33% in the control group,with significant difference(P<0.05).The level of myocardial enzyme after treatment in the observation group was lower than that in the control group,with significant difference(P <0.05). Conclusion FDP can effectively improve the treatment effect in children with VM,and significantly improve electrocardiogram and myocardial enzyme spectrum,it is worthy of clinical promotion and application.