丹红注射液对后循环缺血眩晕病人血液流变学及血脂的影响

The Infuluence of Danhong Injection on Blood Rheology and Blood Lipid in Patients with Posterior Circulation Ischemia

目的观察丹红注射液对后循环缺血(PCI)眩晕病人血液流变学及血脂的影响,探讨丹红注射液治疗PCI眩晕的作用机制。方法将59例PCI眩晕病人随机分为两组,基础治疗相同,对照组予以长春西汀注射液治疗,观察组在对照组的基础上加用丹红注射液,疗程均为2周。观察两组病人的血液流变学、血脂变化及临床疗效和不良反应。结果治疗2周后,观察组总有效率为86.67%,高于对照组的75.86%,差异有统计学意义(P<0.05);观察组血液流变学及血脂改善优于对照组(P<0.05)。两组不良反应轻微。结论丹红注射液治疗PCI眩晕安全有效,其疗效可能与改善病人血液流变学及血脂有关。

Objective To observe the effects of Danhong injection （DHI） in treating patients with posterior circulation ischemia （PCI）. Methods Fifty nine patients with PCI were randomly divided into two groups：control group treated with vinpocetine injection,and treatment group treated with vinpocetine injection plus DHI for 2 weeks.The curative effect was observed, blood rheology and lipid were observed. Results The clinical effective rate in treatment group was higher than that in the control group （86.67% vs 75.86% , P 〈0.05）.There was no differences in adverse reactions between two groups（ P 〉 0 .0 5 ） . After the treatment, the blood rheology （viscosity,low shear viscosity,plasma viscosity and reduced viscosity） and blood lipid in the treatment group were significantly im-proved （ P〈0.05）. Conclusion DHI can improving blood rheology and blood lipid,and is effective and safe on treating PCI.