宁波市HIV感染者梅毒感染及其影响因素分析

Prevalence and influence factors of syphilis among people infected with HIV in Ningbo municipality

目的了解浙江省宁波市人类免疫缺陷病毒(HIV)感染者的梅毒感染情况及其影响因素,为采取相应的干预措施提供参考依据。方法收集2015年5月—2015年12月宁波市艾滋病自愿咨询检测(VCT)门诊和艾滋病专项管理软件登记在册的2 090例HIV感染者的临床病历资料,分析宁波市HIV感染者的梅毒患病情况及其相关影响因素。结果宁波市2 090例HIV感染者中感染梅毒者197例,梅毒感染率为9.4%;多因素非条件logistic回归分析结果显示,年龄≥46岁和性伴数量≥2个是宁波市HIV感染者梅毒感染的危险因素,女性、文化程度初中及以上和采用高效抗逆转录病毒疗法(HAART)治疗是宁波市HIV感染者梅毒感染的保护因素。结论宁波市HIV感染者梅毒患病率较高,性别、年龄、文化程度、性伴数量和是否采用HAART治疗是宁波市HIV感染者梅毒感染的主要影响因素。

Objective To examine the prevalence and influence factors of human immunodeficiency virus （HIV）-syphilis co-infection in Ningbo municipality,Zhejiang province and to provide references for conducting corresponding interventions.Methods A cross-sectional study was performed at HIV voluntary counseling and testing （VCT） clinics in Ningbo municipality from May to December,2015.A total of 2 090 registered adult HIV infected persons were recruited.Electronic questionnaire and Ningbo acquired immunodeficiency syndrome （AIDS）special management registration software were used to collect data on socio-demography and potential risk factors for syphilis infection.Results The prevalence rate of syphilis sero-positive was 9.4% in the participants.The influence factors for HIV-syphilis co-infection included gender,age,education level,the number of sexual partners and whether having highly active antiretroviral therapy （HAART）;the risk factors were having more than 2 sexual partners and at the age of 46 years or older,while the protective factors were female gender,with higher education,and having HAART.Conclusion The prevalence of syphilis is high and gender,age,education level,number of sexual partners,and whether having HAART are main influence factors of syphilis infection among the people infected with HIV in Ningbo municipality.