磁共振MRS与DWI对前列腺中央腺体癌的影像诊断及临床应用的价值探讨

Study on Magnetic Resonance MRS and DWI in Imaging Diagnosis of Prostatic Central Gland Cancer and Clinical Application Value

目的对在前列腺中央腺体癌肿应用磁共振MRS与DWI的影像诊断与临床应用价值进行探讨。方法方便选择2016年4—12月来该院就诊的60例患者进行MRS、DWI扫描,抽取经病理证实前列腺癌(PCa)21例及良性腺体增生(BPH)39例进行MRI与DWI数据分析,测量PCa癌区及BPH外周带、中央腺体的ADC(扩散常数-表观扩散系数)值。结果 21例前列腺癌病灶ADC平均值为(1.16±0.21)×10^(-3)mm^2/s,39例前列腺增生患者的中央腺体ADC平均值为(1.51±0.08)×10^(-3)mm^2/s。前列腺增生患者的ADC值明显要高于前列腺癌区的,数据差异有统计学意义(P<0.05);前列腺癌组CC/C值平均为2.56±1.21,前列腺增生组CC/C值平均为0.81±0.16,两者数据差异有统计学意义(P<0.05)。结论联合应用磁共振MRS与DWI技术,在前列腺中央腺体癌的临床诊断上具有较高价值。

Objective To discuss the magnetic resonance MRS and DWI in imaging diagnosis of prostatic central gland cancer and clinical application value. Methods Convenient selection 60 cases of patients diagnosed in our hospital from April to December 2017 were selected for MRS and DWI scanning, and the 21 PCa cases and 39 BPH cases were confirmed by pathology and selected for MRI and DWI data analysis, and the ADC values in the PCa cancer region, BPH peripheral zone and central gland were measured. Results The average value of ADC of 21 cases of patients with prostatic cancer was obviously higher than that of patients with prostatic hyperplasia[(1.51±0.08)×10^(-3)mm^2/s vs(1.16±0.21)×10^(-3)mm^2/s](P<0.05), and the difference in the average value of CC/C between the prostatic cancer group and the prostatic hyperplasia group had statistical significance[2.56±1.21 vs 0.81±0.16], and the difference had statistical significance(P<0.05). Conclusion The combined application of magnetic resonance MRS and DWI in clinical diagnosis of central gland carcinoma of prostate has a higher value.