黄花三宝木枝叶化学成分的研究

Chemical constituents from twigs of Trigonostemon lutescens

目的研究黄花三宝木Trigonostemon lutescens Y.T.Chang et J.Y.Liang枝叶的化学成分。方法黄花三宝木枝叶95%乙醇提取物的乙酸乙酯部位采用硅胶、Sephadex LH-20和MCI柱进行分离纯化,通过理化性质和波谱数据对所得化合物的结构进行鉴定。结果从中分离出10个化合物,分别鉴定为3-乙酰氧基-齐墩果酸(1)、3-乙酰氧基-12-烯-齐墩果酸甲酯(2)、蒲公英赛酮(3)、spiciflorin(4)、simiarenol(5)、β-谷甾醇棕榈酸酯(6)、3,3',4-O-三甲基鞣花酸(7)、β-谷甾醇(8)、豆甾醇(9)、棕榈酸(10)。结论化合物1~6为首次从三宝木属植物中分离得到,化合物7和9为首次从该植物中分离得到。

AIM To study the chemical constituents from twigs of Trigonostemon lutescens Y. T. Chang et J. Y. Liang. METHODS The ethyl acetate fraction of 95% ethanol extract from T. lutescens twigs was isolated and purified by silica, Sephadex LH-20 and MCI column, then the structures of obtained compounds were identified by physicochemical properties and spectral data. RESULTS Ten compounds were isolated and elucidated as 3-O- acetyloleanolic acid （ 1 ）, methyl 3-acetoxy-12-enly-oleanen-28-oate （2）, taraxerone （3）, spiciflorin （4）, simi- arenol （5）, β-sitosterol palmitate （6）, 3, 3＇, 4-tri-O-methylellagic acid （ 7 ）, β-sitosterol （ 8）, stigamasterol （9）, palmitic acid （10）. CONCLUSION Compounds 1 -6 are isolated from genus Trigonostemon for the first time, compounds 7 and 9 are first obtained from this plant.