隔药饼灸对不同年龄人群机体CD3、CD4及CD8的影响

Effects of Herbal Cake Moxibustion on CD3,CD4,and CD8 in Different Age Groups

目的:通过对神阙、关元等保健穴施以隔药饼灸,观察对不同年龄人群机体CD系列的变化,探讨艾灸调节机体免疫功能的机制。方法:将六味地黄丸中药物按方剂比例配伍,制成药饼,放置于神阙、关元、足三里(双)、脾俞(双)、肾俞(双)穴位上。将0.3 g圆锥形艾炷置于药饼上施灸,每穴灸3壮,隔日1次,共10次。分别在施灸前、后抽静脉血5 m L,观测CD3、CD4、CD8、CD4/CD8的变化并进行比较。结果:青年组隔药饼灸后CD3、CD4、CD4/CD8均较灸前均升高,CD8较灸前降低,差异均无统计学意义(P>0.05)。中年组隔药饼灸后CD3较灸前升高,差异无统计学意义(P>0.05),CD4、CD4/CD8较灸前升高,CD8较灸前降低,差异均有显著统计学意义(P<0.05)。老年组隔药饼灸后CD3、CD4/CD8较灸前均升高,CD8较灸前降低,差异均有显著统计学意义(均P<0.05),CD4较灸略有升高,差异无统计学意义(P>0.05)。结论:隔药饼灸对3个不同年龄段机体免疫功能的调节以中、老年组为显著,对不同年龄组作用机制亦不同。

Objective：To observe the changes of CD series in different age groups after herbal moxibustion on CV 8 （Shenque） and CV 4 （Guanyuan） and so on, and to explore the mechanism of moxibustion regulating body immunity.Methods：Liuwei Dihuang Pill herbal powder were made into herbal mox cake and CV 8 （Shenque）, CV 4 （Guanyuan）, ST 36 （Zusanli）, BL 20 （Pishu） and Bl 23 （Shenshu） were selected.The moxa cone （0.3 g） was placed right on the herbal cake over the selected acupoints and burned.In each treatment, three cones were applied to each acupoint.The treatment was carried out once every other day for 10 times.Each subject was extracted venous blood about 5 ml before and after all the treatment.Results：After the treatment with herbal cake moxibustion, CD3, CD4, and CD4/CD8 were increased （P〉0.05） in young people;in the middle-aged group, CD3 was increased （P〉0.05）, CD4 and CD4/CD8 were increased, however, CD8 was decreased （P〈0.05）;in the elder group, CD3 and CD4/CD8 were increased （P〈0.05）, CD8 was decreased （P〈0.05）, and CD4 had little increase （P〉0.05）.Conclusions：The regulation of herbal cake moxibustion on body immunity in different age groups was significant in the elder group and middle-aged group, and the mechanism was different in each group.