高频超声在婴幼儿体表血管瘤治疗中的应用价值

Application value of high frequency ultrasound in the treatment of infantile hemangioma

目的探讨高频超声在婴幼儿体表血管瘤治疗中的应用价值。方法回顾性分析42例婴幼儿体表血管瘤治疗前后的声像图资料,并按治疗结果分为治疗有效组33例和治疗无效组9例,比较分析两组治疗前后瘤体大小、回声及血流动力学参数(动脉收缩期峰值流速、静脉流速、阻力指数)变化的差异,总结出可靠的超声观察指标。结果与治疗前比较,治疗有效组治疗后19例血流信号减少,全部瘤体厚度减小,31例动脉收缩期峰值流速降低,30例静脉流速降低,29例阻力指数升高,差异均有统计学意义(均P<0.05);瘤体长径和宽径比较差异均无统计学意义。治疗无效组上述各观察指标治疗前后比较差异均无统计学意义。治疗有效组中,治疗6个月患儿瘤体厚度明显减小,与治疗1个月和3个月患儿比较,差异均有统计学意义(均P<0.05)。结论高频超声在婴幼儿体表血管瘤的治疗和随访中有重要的应用价值,其中瘤体厚度的变化是最主要的观察指标。

Objective To investigate the application value of high-frequency ultrasound in the treatment of infantile hemangiomas.Methods Ultrasonographic data before and after treatment were collected from 42 patients with infantile hemangioma,and the treatment results were divided in response group of 33 cases and non-response group of 9 cases.The differences of size,echo and hemodynamic parameters（peak arterial systolic flow velocity,venous velocity,resistance index）were analyzed,the reliable diagnostic indicators for ultrasonographic follow-up were summarized.Results In response group,the blood flow signals were decreased in 19 cases,the thickness of tumor were reduced in all cases,the PSV were reduced in 31 cases,venous velocity were reduced in 30 cases,RI were increased in 29 cases,the differences were statistically significant compared with those before treatment（all P0.05）.while there were no statistical difference in ratios of length and width of tumor.In the nonresponse group,there were no significant changes in any of these observational indicators.After treatment for 6 months,there was significant decrease in tumor thickness,with significant differences from those having treatment for 1 and 3 months respectively.Conclusion High-frequency color Doppler ultrasound had significant application value in the follow-up for treatment of infantile hemangiomas,where changes in tumor thickness provided the primary observational indicator.