尿酸与骨代谢的关系

Uric acid and bone metabolism

骨代谢是指骨中的细胞不停地进行细胞代谢,骨组织细胞之间存在相互作用,骨髓中的红细胞生成细胞、基质细胞也存在相互作用,以进行骨的改建和重建。尿酸是一种体内嘌呤代谢的最终产物,近年来人体内血尿酸水平与心血管事件、中枢系统疾病、代谢综合征、骨代谢异常等疾病的关系备受关注。目前尿酸对骨代谢的影响并不明确。

Bone metabolism is a kind of metabolism in phalangeal cells. The interaction not only exits in the bone cells, also in the bone marrow erythropoietic cells and stromal cell, for rebuilding and reconstructing bone. Uric acid is an end product of purine metabolism in vivo. In recent years, the relationship of uric acid levels with cardiovascular events, central nervous system diseases, metabolic syndrome, bone metabolism and other diseases has attracted much attention. The effect of uric acid on bone metabolism is still not clear.