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加味固肾纳气汤联合金匮肾气丸治疗肾虚型支气管哮喘缓解期患者的疗效及对肺功能及生活质量的影响 被引量:6

Effect of modified Gushen Naqi decoction combined with Jinkui Shenqi pill in the treatment of patients with kidney deficiency type of remission period of bronchial asthma,and its effect on lung function and quality of life
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摘要 目的探讨金匮肾气丸联合加味固肾纳气汤治疗肾虚型支气管哮喘缓解期患者的疗效以及对患者肺功能及生活质量的影响。方法选取2015年4月至2017年2月我院收治的肾虚型支气管哮喘缓解期患者107例,采用随机数字表法分为对照组和研究组。对照组患者(53例)给予金匮肾气丸治疗,研究组患者(54例)在对照组治疗的基础上给予加味固肾纳气汤治疗,比较两组患者的临床治疗效果,比较治疗前及治疗1个月后两组患者的肺功能及生活质量。结果研究组患者的临床治疗效果优于对照组,差异有统计学意义(P<0.05)。治疗1个月后,两组患者FVC、FEV1、PFE、FEV1/FVC均明显升高,研究组患者的肺功能明显优于对照组,差异有统计学意义(P<0.05);两组患者生理机能、社会功能、一般健康状况、精神健康评分均明显升高,研究组患者的生活质量显著高于对照组,差异有统计学意义(P<0.05)。结论与单用金匮肾气丸治疗比较,金匮肾气丸联合加味固肾纳气汤治疗肾虚型支气管哮喘缓解期患者临床效果显著,可更有效地改善患者的肺功能,提高患者的生活质量。 Objective To investigate the effect of modified Gushen Naqi Decoction Combined with Jinkui Shenqi pill in the treatment of patients with kidney deficiency type of remission period of bronchial asthma,and its effect on lung function and quality of life. Methods 107 patients with kidney deficiency type of remission period of bronchial asthma were selected,which were treated in our hospital from April 2015 to February 2017. The random number table was used to divide into the control group and the study group. The control group(53 cases) were given Jinkui Shenqi pill,the study group(54 cases) were treated by modified Gushen Naqi decoction based on the treatment of the control group. The clinical effects of the two groups were compared,and the lung function and quality of life of the two groups were compared before and after 1 months of treatment. Results The clinical effect of the study group was better than that of the control group,and the difference was statistically significant( P〈0. 05). After 1 months of treatment,the FVC,FEV1,PFE and FEV1/FVC in the two groups increased significantly,and the lung function in the study group was significantly better than that in the control group( P〈0. 05). Physiological function,social function,general health status,mental health score of the two groups increased significantly,the quality of life of the study group was significantly higher than that of the control group,the difference was statistically significant( P〈0. 05). Conclusion Effect of modified Gushen Naqi decoction combined with Jinkui Shenqi pill in the treatment of patients with kidney deficiency type of remission period of bronchial asthma is significantly,which better than Jinkui Shenqi pill used only. It can improve the lung function of the patients more effectively and improve the quality of life of the patients.
作者 杨景福 田玉春 赵林 李成玉 马叔荣 于文彦 杜文娟 秦萍艳 YANG Jingfu 1, TIAN Yuchun 2, ZHAO Lin 3, LI Chengyu 1, MA Shurong 1, YU Wenyan 1, DU Wenjuan 1, QIN Pingyan 1(1 Department of pulmonary, 2 laboratory, 3 second surgery, Traditional Chinese Medicine Hospitalof Lintao in Gansu province, Lintao 730500, Chin)
出处 《内科》 2018年第2期160-162,220,共4页 Internal Medicine
关键词 肾虚型支气管哮喘缓解期 治疗 金匮肾气丸 加味固肾纳气汤 肺功能 生活质量 kidney deficiency type of remission period of bronchial asthma Jinkui Shenqi pill Modified Gushen Naqi decoction Pulmonary function Quality of life
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