急性脑梗塞患者检验血清同型半胱氨酸的临床结果分析

Clinical Analysis of Serum Homocysteine in Patients with Acute Cerebral Infarction

目的探析检验急性脑梗塞患者血清同型半胱氨酸指标水平的结果分析。方法随机选择2017年1—12月在该院就诊的急性脑梗塞患者100例为观察组,同期选择该院体检健康者100例为研究对照,检测全部研究对象的血清同型半胱氨酸水平(Hcy),评估观察组的急性脑梗塞的神经缺损程度,评估观察组高同型半胱氨酸血症的发生情况,比较观察组与对照组的血清同型半胱氨酸水平(Hcy),比较观察组不同神经缺损程度患者的血清同型半胱氨酸水平(Hcy)。结果急性脑梗塞患者中诊断为高同型半胱氨酸血症者58例,占58.0%;观察组的血清同型半胱氨酸水平(Hcy)为(29.6±8.5)μmol/L,显著高于对照组的(6.4±1.3)μmol/L,差异有统计学意义(t=26.98、P<0.05);观察组的重度血管狭窄的神经缺损程度评分及同型半胱氨酸水平显著高于中度、轻度,差异有统计学意义(t=6.04,11.32,7.64、22.16,P<0.05),而中度血管狭窄血管狭窄患者的血症患者的神经缺损程度评分及同型半胱氨酸水平显著高于轻度,差异有统计学意义(t=5.17,8.87,P<0.05)。结论急性脑梗塞病人的血清同型半胱氨酸水平偏高,其神经缺损程度与血清同型半胱氨酸水平密切相关。

Objective To analyze the results of testing serum homocysteine levels in patients with acute cerebral infarction.Methods 100 patients with acute cerebral infarction who were treated in the hospital from January 2017 to December 2017 were selected randomly as the observation group. 100 patients with physical examination in this hospital were selected as the control group at the same time. Serum homocysteine was detected in all subjects. Acid level（Hcy）, assessing the degree of neurological deficit in the acute cerebral infarction in the observation group, assessing the occurrence of hyperhomocysteinemia in the observation group, and comparing serum homocysteine levels（Hcy） between the observation group and the control group. To compare serum homocysteine levels（Hcy） in patients with different levels of neurological deficits in the observation group. Results In 58 patients with acute cerebral infarction who were diagnosed as hyperhomocysteinemia,58.0%, and the homocysteine level（Hcy） in the observation group was（29.6±8.5） μmol/L, which was significantly higher than that of the control group. The difference was statistically significant（6.4±1.3） μmol/L in the control group（t=26.98, P〈0.05）. The degree of neurodefection and the level of homocysteine in the severe vascular stenosis were significantly higher in the observation group than in the moderate, mild, the difference was statistically significant（t=6.04,11.32,7.64、22.16,P〈0.05）, and the degree of neurological deficits was scored in hypertensive patients with moderate vascular stenosis and vascular stenosis. The homocysteine level was significantly higher than mild, and the difference was statistically significant（t =5.17,8.87,P〈 0.05）. Conclusion The serum homocysteine level is high in patients with acute cerebral infarction. The degree of neurological deficit is closely related to serum homocysteine level.