湖州市某医院抑郁症患者抑郁水平与快感缺失的相关性分析

Analysis of Correlation Between Depression Level and Anhedonia in Depression Patients of a Hospital in Huzhou City

目的:了解快感缺失在不同抑郁水平抑郁症患者间的差异,分析快感缺失的不同成分与抑郁的关系以及对抑郁的预测能力。方法:采用时间性快感体验量表(TEPS)、汉密尔顿抑郁量表(HAMD)、贝克抑郁问卷(BDI)对湖州市某三甲医院193名符合诊断标准的抑郁症患者进行评估调查。结果:不同抑郁水平的患者之间快感缺失差异显著(F=127. 092,P <0.001)。期待性快感缺失与消费性快感缺失都与抑郁水平显著相关,并对抑郁有显著的预测能力,其中期待性快感缺失的影响程度(std."=0.553,P<0.001)比消费性快感缺失的影响程度(std."=0.395,P<0.001)强。伴随抑郁水平的降低,快感缺失症状在一周后也显著缓解(t=-3.727,P<0.001)。结论:抑郁症患者存在期待性和消费性快感缺失,它们在不同抑郁水平的患者之间差异显著,快感缺失与抑郁水平之间显著相关,对抑郁有一定的预测力,且随抑郁水平的发展而变化。

Objective： To explore the anhedonia change in dillerent depressive severity groups, analyze the relations hetween depression and dillerent anhedonia l）actors which may also predict the development of depression. Methods： 193 depressive padents corresponding to diagnosis standards were recruited to complete the Temporal Experience of Pleasure Scale （TEPS）, Hamihon Depression- Scale （HAMD） and Beck De- pression Inventory （BDI）. Results： The difference of anhedonia in different depressive severity groups was significant （F= 127.092, P= 0.000）. Anticipatory anhedonia and consummatory anhedonia were both significant correlated to the level of depression, and predicted the development of depression. The predict power of anticipatory anhedonia （P = 0.553, P〈 0.001 ） was stronger than consummatory anhedonia （P = 0.395, P〈 0. 001）. The level of anhedonia tested one week later was much lower than belbre, the difference was signilficant （t =-3.727, P= 0.000）. Conclu- sion： Anticipatory anhedonia and consummatory anhedonia both existed in depression patients, but changed in dillerent depressive severity groups with the development of depression symptoms, which could predict the level of depression and be relieved after treatments.