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普通肝素剂量调整在连续性血液净化中的应用及护理 被引量:1

Application and nursing of unfractionated heparin dose adjustment in continuous blood purification
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摘要 目的探究普通肝素剂量调整在连续性血液净化中的应用效果及护理措施。方法选取湖州市中心医院2014年1月~2017年1月进行连续性血液净化治疗的94例患者,按照时间先后,将患者分为观察组和对照组,每组各47例,所有患者均采取连续性血液净化治疗,对照组患者肝素首剂1000U,持续500U/h量不变;观察组患者肝素首剂1000U,初始维持量500U/h,随后每4h调整一次肝素用量;对比2组患者的治疗效果。结果观察组治疗时间(23.73±18.97)h明显高于对照组(16.28±10.74)h(P<0.05);观察组滤器凝血例数明显少于对照组(P<0.05)。结论在连续性血液净化中调整普通肝素剂量能够延长治疗时间,提升治疗效果,延长滤器寿命。 Objective To explore the application effect and nursing measures of unfractionated heparin dose adjustment in continuous blood purification.Methods From January2014to January2017in Huzhou Central Hospital,94patients of continuous blood purification treatment according to the time sequence,were divided into observation group(n=47)and control group(n=47),all patients were treated by continuous blood purification treatment,the control group of heparin in patients with an initial dose of1000U,continuous500U/h constant patients in the observation group;the first dose of heparin1000U,initial maintenance dose of500U/h,then each4h adjusted once the amount of heparin;compared two groups of patients.Results The observation group treatment time(23.73±18.97)h was significantly higher than the control group(16.28±10.74)h,significant difference(P<0.05);filter clotting in observation group were significantly less than the control group,there was statistical significance(P<0.05).Conclusion Adjusting the dose of unfractionated heparin in continuous blood purification can prolong the treatment time,improve the treatment effect and prolong the life of filter.
作者 吴辰 朱云 WU Chen;ZHU Yun(212 Lesion, Huzhou Central Hospital, Huzhou 313000, China)
机构地区 湖州市中心医院
出处 《中国生化药物杂志》 CAS 2017年第11期425-426,共2页 Chinese Journal of Biochemical Pharmaceutics
关键词 肝素 连续性血液净化 治疗时间 heparin continuous blood purification treatment time
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