摘要
目的观察柴胡疏肝散加减治疗肝胃不和型反流性咽炎的疗效。方法将153例临床诊断为肝胃不和型反流性咽炎患者随机分为三组,各51例,治疗组给予柴胡疏肝散加减治疗,观察组给予柴胡疏肝散+奥美拉唑治疗,对照组给予奥美拉唑治疗,疗程为8周,比较三组的临床疗效。结果治疗前后比较:三组的反流症状指数量表(RSI)、反流体征量表(RSF)评分均有改善;治疗组与对照组比较,差异无统计学意义(P> 0.05),观察组与治疗组,差异有统计学意义(P <0.05)。治疗1周时咽异物感的缓解率:治疗组87.76%(43/49),观察组91.67%(44/48),对照组70.83%(34/48),与对照组比较,治疗组及观察组的缓解率更高,差异有统计学意义(P <0.05)。结论柴胡疏肝散加减对肝胃不和型反流性咽炎有较好的疗效,单用可以达到与奥美拉唑相似的效果,奥美拉唑联用柴胡疏肝散可以进一步提高疗效,特别是在缓解咽异物感症状上具有一定优势。
Objective To study the clinical efficacy of modified Chaihushugan powder in the treatment of Reflux Pharyngitis of Liver Stomach Disharmony Type. Methods A total of 153 cases with reflux pharyngitis of liver stomach disharmony type were divided into treatment group,observation group and control group,with 51 cases in each group.The treatment group was treated with ChaihuShugan Powder,the observation group was treated with ChaihuShugan Powder plus proton pump inhibitor(PPI) Omeprazole,while the control group was treated with PPI only.The course of treatment was 8 weeks,and the clinical effects of the three groups were compared. Results Comparison before and after treatment:RSI and RSF scores of the three groups were improved.Comparison between groups:there was no significant difference between the treatment group and the control group (P>0.05),there were statistically significant differences between the observation group and the treatment group(P<0.05).The remission rate of pharyngeal foreign body sensation at 1 week after treatment:87.76%(43/49) in the treatment group,91.67%(44/48) in the observation group,and 70.83%(34/48) in the control group.Compared with the control group,the remission rate of the treatment group and the observation group was higher,and the difference was statistically significant (P<0.05). Conclusion Chaihushugan powder has better curative effect on disharmony regurgitation pharyngitis of liver and stomach,which can achieve similar effect with omeprazole alone,and omeprazole combined with chaihushugan powder can further improve the curative effect,especially in alleviating symptoms of foreign body sensation in pharynx.
作者
陈学华
陈舒
陈俊曦
钟艳萍
CHEN Xuehua;CHEN Shu;CHEN Junxi;ZHONG Yanping(Department of Otorhinolaryngology,Foshan Hospital of Traditional Chinese Medicine,Foshan 528000,China)
出处
《中国医药科学》
2019年第5期42-44,共3页
China Medicine And Pharmacy
基金
广东省中医药局科研课题(20161243)
关键词
柴胡疏肝散
反流性咽炎
质子泵抑制剂
Chaihushugan powder
Reflux Pharyngitis
Proton pump inhibitor