摘要
Summary of main observation and conclusion A rigid C2-symmetric chiral bipyridine ligand Z-bpy with a triptycene-like backbone was designed and synthesized from simple chemicals in a scalable route.Using this new ligand,copper(Ⅰ) catalyzed cyclopropanation of styrenes with commercial ethyl diazoacetate produced various corresponding cyclopropanes in high yields,diastereoselectivity and enantioselectivity up to 97% ee.
基金
provided by the National Natural Science Foundation of China (Nos.21672168 and 21702157)
China Postdoctoral Science Foundation (No.2017M623148)
the National Postdoctoral Program for Innovative Talents (No.BX201600122)
Key Laboratory Construction Program of Xi'an Municipal Bureau of Science and Technology (No.201805056ZD7CG40).
