超声诊断在出生缺陷产前筛查中的应用效果分析

Ultrasound diagnosis in prenatal screening of birth defects

目的:评估超声检测方法于出生缺陷临床产前筛查中的使用效果。方法:对2018年1月—12月本医院接受出生缺陷临床产前筛查的1000例孕妇实施项目指标研究,均开展产前超声检测,评估临床产前超声筛查出生缺陷结果、临床产后确诊出生缺陷结果。结果:1000例孕妇中,临床产前超声筛查检出出生缺陷合计率是1.2%(12/1000),其中,胸腹壁缺损内脏外翻33.33%(4/12),单腔心25.00%(3/12),脑膨出41.67%(5/12);临床产后确诊出生缺陷合计率是1.3%(13/1000),其中,胸腹壁缺损内脏外翻30.77%(4/13),单腔心23.08%(3/13),脑膨出38.46%(5/13),肛门闭锁7.69%(1/13);临床产前超声诊断检出出生缺陷准确性是92.30%(12/13),临床产前超声诊断漏诊合计率是7.69%(1/13)。结论:在出生缺陷临床产前筛查中采用超声检测方法体现出较好的诊断价值。

Objective To evaluate the effectiveness of ultrasound in prenatal screening of birth defects.Methods 1000 pregnant women who received clinical prenatal screening for birth defects in our hospital from January 2018 to December 2018 were studied.Prenatal ultrasound testing was carried out to evaluate the results of clinical prenatal ultrasound screening for birth defects and clinical postnatal diagnosis of birth defects.Results Among 1000 pregnant women,the total rate of birth defects detected by clinical prenatal ultrasound screening was 1.2%(12/1000),of which 33.33%(4/12)had visceral valgus,25.00%(3/12)had single chamber heart,41.67%(5/12)had encephalocele,and 1.3%(13/1000)had clinically confirmed birth defects,among which,the total rate of chest and abdominal wall defects was 1.3%(13/1000).Visceral valgus 30.77%(4/13),single chamber heart 23.08%(3/13),encephalocele 38.46%(5/13)and anal atresia 7.69%(1/13);the accuracy of prenatal ultrasound in detecting birth defects was 92.30%(12/13),and the total missed diagnosis rate of clinical prenatal ultrasound was 7.69%(1/13).Conclusion Ultrasound detection is of better diagnostic value in clinical prenatal screening of birth defects.