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Probiotic mixture VSL#3:An overview of basic and clinical studies in chronic diseases 被引量:11

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摘要 Probiotics are known as“live microorganisms”and have been proven to have a health effect on hosts at the proper dose.Recently,a kind of probiotic mixture including eight live bacterial strains,VSL#3,has attracted considerable attention for its combined effect.VSL#3 is the only probiotic considered as a kind of medical food;it mainly participates in the regulation of the intestinal barrier function,including improving tight junction protein function,balancing intestinal microbial composition,regulating immune-related cytokine expression and so on.The objective of this review is to discuss the treatment action and mechanism for the administration of VSL#3 in chronic diseases of animals and humans(including children).We found that VSL#3 has a therapeutic or preventive effect in various systemic diseases per a large number of studies,including digestive systemic diseases(gastrointestinal diseases and hepatic diseases),obesity and diabetes,allergic diseases,nervous systemic diseases,atherosclerosis,bone diseases,and female reproductive systemic diseases.
出处 《World Journal of Clinical Cases》 SCIE 2020年第8期1361-1384,共24页 世界临床病例杂志
基金 the Innovative Talent Support Program of the Institution of Higher Learning in Liaoning Province,No.2018-478 the Innovative Talents of Science and Technology Support Program of Young and Middle People of Shenyang,No.RC170446.
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