拔毒生肌活血散联合依帕司他对糖尿病足感染干预研究

Interventional Study on Diabetic Foot Infection Using Badu Shengjihuoxue Powder and Epalrestat

目的:探究糖尿病足感染采取拔毒生肌活血散联合依帕司他的治疗效果。方法:选取笔者所在医院2018年1月-2019年8月收入的糖尿病足感染患者84例,按照随机数字表法分为两组,各42例,对照组采取依帕司他治疗,观察组在对照组基础上联合拔毒生肌活血散治疗,比较两组治疗效果。结果:观察组治疗时间、住院时间均短于对照组,踝肱指数(ABI)高于对照组,差异均有统计学意义(P<0.05);观察组肉芽组织0级、1级患者占比低于对照组,2级、3级、4级患者占比高于对照组,差异均有统计学意义(P<0.05);观察组治疗总有效率为95.24%,高于对照组的78.57%,差异有统计学意义(P<0.05)。结论:糖尿病足治疗上,采取拔毒生肌活血散联合依帕司他干预,临床治疗效果显著,能缩短治疗所需时间,改善预后,值得应用。

Objective:To study the effects of Badu Shengjihuoxue Powder and Epalrestat in diabetic foot.Method:A total of 84 diabetic foot infection patients treated in our hospital from January 2018 to August 2019 were selected and randomly assigned to the control group (42 cases) and the observation group (42 cases).The control group took Epalrestat,the observation group took Epalrestat and Badu Shengjihuoxue Powder.The therapeutic effects of two groups were compared.Result:The treatment time and hospital stay in the observation group were shorter than those in the control group,the ankle brachial index (ABI) was higher than that in the control group,the differences were statistically significant (P<0.05).The proportion of patients with grade 0 and grade 1 of granulation tissue in the observation group was lower than that in the control group,the proportion of patients with grade 2,grade 3 and grade 4 of granulation tissue in the observation group was higher than that in the control group,the differences were statistically significant (P<0.05).The total effective rate in the observation group (95.24%) was significantly higher than that in the control group (78.57%),the difference was statistically significant (P<0.05).Conclusion:Badu Shengjihuoxue Powder and Epalrestat has obvious effects to shorten the treatment time and improve the clinical prognosis.It is worthy of application.