自拟化痰通络方治疗风痰阻络型急性脑梗死的临床效果

Clinical effect of Self-made Huatan Tongluo Prescription in the treatment of acute cerebral infarction with syndrome of wind-phlegm obstructing collateral

目的观察自拟化痰通络方治疗风痰阻络型急性脑梗死患者的临床效果。方法选取2019年1月至2020年8月北京中西医结合医院脑病科收治的60例急性脑梗死患者作为研究对象,根据随机数字表法将其分为对照组和治疗组,每组各30例。两组均予以常规治疗,治疗组在对照组的基础上加用化痰通络方,总疗程为4周。观察两组患者治疗前后的中医证候积分、美国国立卫生研究院卒中量表(NIHSS)评分、巴氏指数(BI)评分,比较两组临床疗效差异。结果治疗后,两组患者中医证候积分、NHISS评分均较治疗前降低,BI评分较治疗前升高,且治疗组中医证候积分、NHISS评分显著低于对照组,BI评分显著高于对照组,差异均有统计学意义(P <0.05)。治疗组临床疗效显著优于对照组(P <0.05)。结论自拟化痰通络方治疗风痰阻络型急性脑梗死效果显著,可以明显改善急性脑梗死患者神经功能缺损症状,缓解中医证候,提高患者生活质量。

Objective To observe the clinical effect of Self-made Huatan Tongluo Prescription in the treatment of acute cerebral infarction patients with syndrome of wind-phlegm obstructing collateral.Methods From January 2019 to August 2020,a total of 60 patients with acute cerebral infarction admitted to Department of Encephalopathy in Beijing Hospital of Integrated Traditional Chinese and Western Medicine were selected as the research subject.They were divided into control group and treatment group according to the random number table method,with 30 cases in each group.Both groups were given conventional treatment,on the basis of the control group,the treatment group was added with Huatan Tongluo Prescription,the total course of both groups was four weeks.Traditional Chinese medicine(TCM)syndrome scores,National Institutes of Health stroke scale(NHISS) scores,Barthel index(BI) scores before and after treatment were observed in both groups,and the difference of clinical efficacy in both groups was compared.Results After treatment,TCM syndrome scores and NHISS scores in both groups were lower than those before treatment,BI scores were higher than those before treatment,and TCM syndrome score and NHISS score in the treatment group were significantly lower than those in the control group,BI score was significantly higher than that of the control group,the differences were statistically significant(P < 0.05).The clinical efficacy of the treatment group was significantly better than that of the control group(P < 0.05).Conclusion The self-made Huatan Tongluo Prescription has a remarkable effect in the treatment of acute cerebral infarction with syndrome of wind-phlegm obstructing collateral,which can obviously improve the neurological deficit symptoms of acute cerebral infarction patients,relieve TCM syndrome,and increase the patients’ quality of life.