摘要
Cardiovascular disease(CVD)is a major cause of mortality and morbidity worldwide.In China,it is estimated that 330 million people are CVD patients.With the rapid aging of populations around the world,the number of CVD patients and death due to CVD are continuously rising.1 Exercise and physical activity have been recognized as economical and effective ways to enhance cardiovascular health and reduce CVD.Pathways mediating the cardiovascular benefits of exercise are promising therapeutic targets for CVD.