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Fluorescence lifetime imaging of fluorescent proteins as an effective quantitative tool for noninvasive study of intracellular processes 被引量:3

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摘要 Fluorescence litime imaging(FLIM)is an effective noninvasive bioanalytical tol based onmeasuring fuorescent lifetime of fuorophores.A growing number of FLIM studies utilizes ge-netically engineered fluorescent proteins targeted to specific subcellular structures to probe localmolecular environment,which opens new directions in cell science.This paper highlights theunconventional applications of FLIM for studies of molecular processes in diverse organelles oflive cultured cells.
出处 《Journal of Innovative Optical Health Sciences》 SCIE EI CAS 2018年第1期13-21,共9页 创新光学健康科学杂志(英文)
基金 supported by the National Basic Research Program of China(2015CB352005) the National Natural Science Foundation of China(61525503/61378091/61620106016) Guangdong Natural Science Foundation Innovation Team(2014A030312008) Hong Kong,Macao and Taiwan cooperation innovation platform and major projects of international cooperation in Colleges and Universities in Guangdong Province(2015KGJHZ002) Shenzhen Basic Research Project(JCYJ20150930104948169/JCYJ20160328144746940/GJHZ 20160226202139185).
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