摘要
智能药物传输载体是生物材料领域的前沿研究方向,将其融入本科教学是践行科教融合和培养创新型人才的重要途径。通过简便化和模块化设计,将较为成熟的科研实例聚乙二醇-聚天冬氨酸(苄胺-二异丙基氨基乙酯)[PEG-PAsp(Bza-DIP)]的合成与评价设计成综合实验,与传统药物传输载体实验相比,更侧重于训练学生掌握智能响应性聚合物的合成表征和药物控释性能的评价方法,使学生系统了解先进生物材料研究技术和启发学生创新性思维。为在高年级本科实验课程融入前沿研究技术提供新思路和新方法,利于创新型人才的培养。
Integrating smart drug delivery carrier,which is considered as one of frontier fields in biomaterials science,into undergraduate education is an important approach to practice the integration ideal of science and education and cultivate innovative talent.The relative mature research work about smart drug delivery carrier polyethyleneglycol-polyaspartic acid(Benzylamine-diisopropylaminoethyl)(PEG-PAsp(Bza-DIP))is used to build integrated experiment.Compared to the integrated experiment about conventional drug delivery carrier,this experiment prefers to train student to master the experimental skills of synthesis,characterization,and functional evaluation of stimulus-responsive polymer,which makes the student to learn advanced biomaterials research technology and develop innovation thinking.This integrated experiment provides a new strategy for integration of science and education,which is favor of cultivating innovative talent.
作者
程度
余东升
陈极峰
CHENG Du;YU Dongsheng;CHEN Jifeng(School of Materials Science and Engineering,Sun Yat-sen University,Guangzhou 510275,China)
出处
《实验室研究与探索》
CAS
北大核心
2023年第3期171-176,共6页
Research and Exploration In Laboratory
基金
国家自然科学基金面上项目(21875289)。
关键词
智能药物传输载体
生物材料
药物释放
综合实验
smart drug delivery carrier
biomaterials
controlled drug release
integrated experiment
