不同胆道引流方式在胆道再手术患者中的应用效果分析

Application Effect Analysis of Different Biliary Drainage Methods in Patients Undergoing Biliary Reoperation

目的:探讨不同胆道引流方式在胆道再手术患者中的应用效果。方法:选取2012年1月—2022年1月诸城市昌城卫生院收治的116例胆道再手术患者作为研究对象,以计算机随机分组法分为对照组与试验组,各58例。试验组实施胆道外引流,对照组实施胆道内引流。比较两组治疗效果、并发症发生情况、炎性因子水平、生活质量。结果:试验组治疗总有效率高于对照组,差异有统计学意义(P=0.015)。试验组并发症发生率低于对照组,差异有统计学意义(P=0.009)。术前,两组C反应蛋白(CRP)、白细胞计数(WBC)、白细胞介素-6(IL-6)、肿瘤坏死因子(TNF)水平比较,差异无统计学意义(P>0.05);术后,试验组CRP、WBC、IL-6、TNF水平均低于对照组,差异有统计学意义(P<0.001)。术前,两组各项生活质量评分比较,差异无统计学意义(P>0.05);出院时,试验组各项生活质量评分均高于对照组,差异有统计学意义(P<0.001)。结论:胆道内引流在胆道再手术患者中的应用效果优于胆道外引流,可提高治疗效果,减少并发症,降低炎性因子水平,提高生活质量。

Objective:To explore the application effect of different biliary drainage methods in patients undergoing biliary reoperation.Methods:From January 2012 to January 2022,116 patients with reoperation of biliary tract in Zhucheng Changcheng Hospital were selected as the study subjects.The patients were divided into control group and experimental group according to the method of computer randomization method,with 58 cases in each group.The experimental group implemented external biliary drainage and the control group implemented internal biliary drainage.The treatment effect,occurrence of complications,inflammatory factor levels,and quality of life in the two groups were compared.Results:The total effective rate of treatment in the experimental group was higher than that in the control group,and the difference was statistically significant(P=0.015).The incidence of complications in the experimental group was lower than that in the control group,and the difference was statistically significant(P=0.009).Before surgery,there was no significant difference in the levels of C-reactive protein(CRP),white blood cell count(WBC),interleukin-6(IL-6)and tumor necrosis factor(TNF)between the two groups(P>0.05).After surgery,the levels of CRP,WBC,IL-6 and TNF in the experimental group were lower than those in the control group,and the difference was statistically significant(P<0.001).Before surgery,there was no significant difference in the quality of life scores between the two groups(P>0.05).At discharge,the quality of life scores in the experimental group were higher than those in the control group,and the difference was statistically significant(P<0.001).Conclusion:The application effect of internal biliary drainage is better than that of external biliary drainage in patients undergoing biliary reoperation,which can improve the therapeutic effect,reduce the complications,decrease the levels of inflammatory factors,and increase the quality of life.