南昌市子宫颈癌疑似病例检查结果及其发病影响因素logistic回归分析

The Results of Suspected Cases of Cervical Cancer in Nanchang City and Its Influencing Factors by logistic Regression

目的:分析南昌市子宫颈癌疑似患者的最终检查结果,并采用多因素logistic回归分析探讨发病的影响因素。方法:选择2019年5月—2021年4月南昌市子宫颈癌筛查女性8938例为对象,均完成液基薄层细胞学及高危型人乳头瘤病毒检查,对于疑似患者行病理组织检查,根据检查结果分为子宫颈癌组与非子宫颈癌组。查阅两组临床资料,并完成单因素和多因素logistic回归分析。结果:8938例南昌市子宫颈癌筛查女性均完成子宫颈癌筛查,最终确诊子宫颈癌37例,确诊率为0.41%。单因素结果表明,子宫颈癌组初次性交年龄<20岁、口服避孕药、子宫颈炎的比例高于非子宫颈癌组;运动、采取避孕套防护、性生活注意卫生比例低于非子宫颈癌组(P<0.05);多因素logistic回归分析结果表明,初次性交年龄≥20岁[B=-2.985,OR=0.051,95%CI(0.015,0.167)]、运动[B=-2.252,OR=0.105,95%CI(0.037,0.300)]、采取避孕套防护[B=-3.205,OR=0.041,95%CI(0.009,0.184)]、性生活注意卫生[B=-1.819,OR=0.162,95%CI(0.060,0.440)]是南昌市女性子宫颈癌发病的保护因素(P<0.05);而口服避孕药物[B=3.700,OR=40.436,95%CI(12.497,130.838)]、子宫颈炎[B=4.631,OR=102.577,95%CI(31.634,332.621)]是南昌市女性子宫颈癌发病的危险因素(P<0.05)。结论:南昌市女性的子宫颈癌检出率较高,且疾病发生受较多因素影响,应根据子宫颈癌发生危险因素采取相应的干预措施,以降低子宫颈癌发生率。

Objective:To analyze the final examination results of suspected patients with cervical cancer in Nanchang city,and the influencing factors of the disease by multivariate logistic regression analysis were discussed.Method:A total of 8,938 women with cervical cancer screening in Nanchang from May 2019 to April 2021 were selected as subjects,all of whom completed liquid-based thin-layer cytology and high-risk human papilloma virus examination,and the suspected patients underwent pathological examination,and were divided into cervical cancer group and non-cervical cancer group according to the examination results.The clinical data of the two groups were consulted,and univariate and multivariate logistic regression analysis was completed.Result:A total of 8,938 cervical cancer screening women in Nanchang City completed Cervical cancer screening,and 37 cervical cancer were finally diagnosed,with a diagnosis rate of 0.41%.The single factor results showed that the proportion of the first sexual intercourse age<20 years,oral contraceptives,and cervicitis in the cervical cancer group were higher than those in the non cervical cancer group,the proportions of exercise,condom protection and attention to health in sexual life were lower than those in the non cervical cancer group(P<0.05).Multivariate logistic regression analysis showed that the age of first sexual intercourse≥20 years[B=-2.985,OR=0.051,95%CI(0.015,0.167)],exercise[B=-2.252,OR=0.105,95%CI(0.037,0.300)],use condoms[B=-3.205,OR=0.041,95%CI(0.009,0.184)],pay attention to hygiene in sex life[B=-1.819,OR=0.162,95%CI(0.060,0.440)]were the protective factor of cervical cancer in women in Nanchang(P<0.05).Oral contraceptives[B=3.700,OR=40.436,95%CI(12.497,130.838)],cervicitis[B=4.631,OR=102.577,95%CI(31.634,332.621)]were the risk factor of cervical cancer in women in Nanchang(P<0.05).Conclusion:The detection rate of cervical cancer in women in Nanchang is high,and the occurrence of the disease is affected by many factors.Corresponding intervention measures should be taken according to the risk factors of cervical cancer to reduce the incidence of cervical cancer.