腹泻型肠易激综合征患者的明尼苏达多相人格测验结果分析

Study on results of patients with diarrhea-predominant irritable bowel syndrome examined by Minnesota Multiphasic Personality Inventory

目的探索腹泻型肠易激综合征(IBS-D)患者的明尼苏达多相人格特点及其与临床特征的关系。方法前瞻性选取2020年4月至2022年12月首都医科大学附属北京世纪坛医院神经和精神科门诊招募的59例IBS-D患者作为病例组,同期招募的健康者41名作为对照组。采用明尼苏达多相人格测试问卷对病例组和对照组进行人格测验,比较两组效度量表4个效度因子和10个临床因子的分值,并将患者的临床特征和量表得分进行相关性分析。结果IBS-D患者的疑病(Hs)、抑郁(D)、癔症(Hy)、心理变态(Pd)、偏执(Pa)、精神衰弱(Pt)、精神分裂(Sc)、社会内向(Si)、防卫(K)因子分显著高于对照组,差异均有统计学意义(P<0.05),疑病(Hs)、抑郁(D)、癔症(Hy)因子均分大于60分。剖析图测图高峰依次为癔症(Hy)、疑病(Hs)和抑郁(D);患者组的年龄与说谎(L)、防卫(K)因子呈正相关(r=0.298、0.300,P=0.022、0.021),年龄与偏执(Pa)、精神衰弱(Pt)因子呈负相关(r=-0.293、-0.262,P=0.024、0.045),IBS患者症状严重程度与抑郁(D)、癔症(Hy)因子呈负相关(r=-0.332、-0.279,P=0.010、0.033)。结论IBS-D患者共病的精神障碍以焦虑障碍和心境障碍为主,可能存在躯体化、焦虑抑郁和神经质的人格特点。

Objective To explore the personality profile of patients with irritable bowel syndrome and its relationship with clinical characteristics.Methods From April 2020 to December 2022,59 IBS-D patients recruited from the Department of Neurology and Psychiatry,Beijing Shijitan Hospital,Capital Medical University were prospectively selected as the case group,while 41 healthy individuals recruited during the same period served as the control group.The case group and control group were assessed conduct personality tests by Minnesota Multiphasic Personality Inventory(MMPI)questionaries.The scores of four validity scales and ten clinical scales were compared between these two groups.Then the relationship between those scales and clinical characteristics of patients with IBS were analyzed.Results In comparison with control group,hypochondria(Hs),depression(D),hysteria(Hy),psychopathy(Pd),paranoia(Pa),mental weakness(Pt),schizophrenia(Sc),social introversion(Si),and defense(K)scales of IBS-D patients were significantly higher,the differences were statistically significant(P<0.05),among the clinical scales,hypochondria(Hs),depression(D)and hysteria(Hy)scale scores were higher than 60.The peak values of profiles were hysteria(Hy),Hs and depression(D)scale scores in turn.There was a positive correlation between age with lying(L)and defense(K)factors(r=0.298,0.300,P=0.022,0.021),while there was negative correlation between age with paranoia(Pa)and mental weakness(Pt)factors(r=-0.293,-0.262,P=0.024,0.045).There was negative correlation between the severity of symptoms in IBS patients with depression(D)and hysteria(Hy)factors(r=-0.332,-0.279,P=0.010,0.033)in patients with IBS-D.Conclusion The comorbid mental disorders of IBS-D patients are mainly anxiety disorders and mood disorders,and there may be somatization,anxiety,depression and neurotic personality characteristics.