摘要
Dear Editor,Platelets are circulating anucleate cytoplasmic fragments of megakaryocytes and characterized by their functions in wound healing and vascular integrity maintenance.Increasing evidence highlights the extensive reciprocal signaling interactions between platelets and tumor cells(Haemmerle et al.,2018).Tumor cells activate and aggregate platelets to sustain proliferation(Cho et al.,2012),resist apoptosis,and promote metastasis(Haemmerle et al.,2017).
基金
supported by the National Science and Technology Major Sub-Project (2018ZX10301402-002)
National Natural Science Foundation of China (81772787,82072889,31822030,and 31771458)
Technical Innovation Special Project of Hubei Province (2018ACA138)
Fundamental Research Funds for the Central Universities (2019kfyXMBZ024)
Wuhan Municipal Health Commission (WX18Q16).
