老年肺癌化疗患者化疗相关性味觉改变与生存质量的Pearson相关分析

Pearson Correlation Analysis on Chemotherapy-related Taste Changes and Quality of Life in Elderly Patients with Lung Cancer Undergoing Chemotherapy

目的:基于Pearson相关分析,探讨老年肺癌化疗患者化疗相关性味觉改变(CITA)与生存质量的关系。方法:采用简单随机抽样法选择2021年1月1日~2022年12月31日收治的老年肺癌化疗患者112例作为研究对象。采用一般资料调查表、化疗相关性味觉改变量表(CiTAS)、肺癌患者生命质量测定量表(QLICP-LU)对患者进行信息收集,另采用SPSS 26.0软件对患者CITA与生存质量进行Pearson相关分析。结果:本研究发放问卷112份,其中2份问卷填写过程中受到外界人为因素干扰,予以剔除,回收有效问卷110份,回收有效率为98.21%。本研究110例患者的CiTAS总分范围4.17~7.60分,中位CiTAS总分为6.13(5.53,6.23)分。不同性别、年龄、TNM分期、口腔清洁方式、化疗方案、吸烟史情况的老年肺癌化疗患者,CiTAS和QLICP-LU总分差异无统计学意义(P>0.05);不同口腔干燥情况、口腔疼痛情况的老年肺癌化疗患者,CiTAS和QLICP-LU总分差异有统计学意义(P<0.01)。老年肺癌化疗患者CiTAS各领域评分及总分与QLICP-LU各领域评分及总分均呈现负相关(r=-0.408~-0.853,P<0.01)。结论:老年肺癌化疗患者CITA与生存质量关系紧密,且目前老年肺癌化疗患者CITA较为严重,根据引起CITA的主要因素制订并实施相应护理措施,有助于改善患者味觉变化,对提高患者生存质量也有积极影响。

Objective:To explore the relationship between chemotherapy-related taste changes and quality of life in elderly patients with lung cancer undergoing chemotherapy based on Pearson correlation analysis.Methods:A simple random sampling method was used to select 112 elderly patients with lung cancer undergoing chemotherapy from January 1,2021 to December 31,2022 as the research subjects.General information questionnaire,Chemotherapy induced Taste Alternation Scale(CiTAS),Quality of Life Instruments for Cancer Patients-Lung Cancer(QLICP-LU)were used to conduct information on patients SPSS 26.0 was used to analyze the chemotherapy-related taste changes and quality of life in patients with Pearson correlation.Results:In this study,112 questionnaires were distributed,2 of which were interfered by external human factors during the filling process and were eliminated.110 valid questionnaires were recovered,and the recovery rate was 98.21%.The CiTAS total scores of 110 patients in this study ranged from 4.17 to 7.60 points,and the median CiTAS total scores were 6.13(5.53,6.23)points.There was no significant difference in the total scores of CiTAS and QLICP-LU among elderly patients with lung cancer chemotherapy with different gender,age,TNM stage,oral cleaning method,chemotherapy regimen,and smoking history(P>0.05).The total scores of CiTAS and QLICP-LU were significantly different in elderly patients with lung cancer undergoing chemotherapy(P<0.01).The CiTAS scores and total scores in each field of elderly patients with lung cancer undergoing chemotherapy were negatively correlated with the scores in each field and total score of QLICP-LU(r value=-0.408~-0.853,P<0.01).Conclusion:Chemotherapy-related taste changes in elderly patients with lung cancer undergoing chemotherapy are closely related to quality of life.At present,chemotherapy-related taste changes in elderly lung cancer patients undergoing chemotherapy are more serious.Formulating and implementing corresponding nursing measures according to the main factors causing chemotherapy-related taste changes will help to improve the taste changes of patients,and also have a positive impact on improving their quality of life.