补肾启枢强心颗粒治疗慢性心力衰竭临床观察

Bushen Qishu Qiangxin Granules in the Treatment of Chronic Heart Failure

目的观察补肾启枢强心颗粒对慢性心力衰竭的临床疗效。方法选取120例江西中医药大学附属医院心血管科2019年1月—2020年12月收治的住院患者,采用随机数字表分为治疗组和对照组,各60例,对照组常规西药治疗,治疗组在常规西药治疗基础上加用补肾启枢强心颗粒,疗程8周。观察比较2组患者中医证候积分、左室射血分数、左室舒张末期内径、左室收缩末期内径、心功能分级变化、脑钠肽水平、6 min步行距离、明尼苏达生活质量量表调查积分等的改善情况。结果治疗组疗效明显优于对照组,差异有统计学意义(P<0.05)。结论补肾启枢强心颗粒治疗慢性心力衰竭临床效果显著,值得推广应用。

Objective To observe the clinical effect of Bushen Qishu Qiangxin granule on chronic heart failure.Methods A total of 120 inpatients admitted to Affiliated Hospital of Jiangxi University of Chinese Medicine from January 2019 to December 2020 were selected and divided into the treatment group and the control group by random number table,with 60 cases in each group.The control group received conventional Western medicine treatment,and the treatment group received Bushen Qishu Qiangxin granule on the basis of conventional Western medicine treatment.The course of treatment was 8 weeks.The improvement of TCM syndrome score,left ventricular ejection fraction,left ventricular end-diastolic diameter,left ventricular end-systolic diameter,cardiac function grading,brain natriuretic peptide(BNP)level,6-min walking distance and Minnesota Quality of Life scale score were observed and compared between the two groups.Results The therapeutic effect of the treatment group was significantly better than that of the control group,and the difference was statistically significant(P<0.05).Conclusion Bushen Qishu Qiangxin granule has significant clinical effects in the treatment of chronic heart failure and is worthy of popularization and application.