摘要
目的基于熵权逼近理想解排序(TOPSIS)法,综合评价不同产地西红花质量,为该药材的质量综合评价和优质产地筛选提供依据。方法采用高效液相色谱(HPLC)波长切换法测定苦番红花素、西红花苷-Ⅰ、西红花苷-Ⅱ和西红花苷-Ⅲ含量,以4种成分总含量、干燥失重、总灰分、吸光度和浸出物作为评价指标,以熵权法计算各指标权重,结合TOPSIS法,对西红花质量进行综合评价。结果熵权TOPSIS法分析结果显示,浙江、西藏、安徽、江苏、上海产西红花的相对贴近度(C_(i))均值分别为0.654、0.396、0.426、0.326、0.341,浙江产西红花整体质量最佳。结论建立的熵权TOPSIS法客观、全面、有效,可用于西红花质量综合评价。
Objective To comprehensively evaluate the quality of Croci Stigma from different regions by using the entropy weighted TOPSIS,and to provide evidence for the quality evaluation and regions selection of Croci Stigma.Methods The contents of picrocrocin,crocin I,crocin II and crocin III were determined by HPLC wavelength switching method.The total content of four components,loss on drying,total ash,absorbance and extract were chosen as detection indexes for Croci Stigma,and the weight was calculated by entropy weight method,and the indexes were statistically analyzed by TOPSIS method.The quality of Croci Stigma was comprehensively evaluated.Results The analysis results of entropy weighted TOPSIS method showed that the mean values of relative closeness(C_(i))values of Croci Stigma from Zhejiang,Tibet,Anhui,Jiangsu provinces and shanghai city were 0.654,0.396,0.426,0.326 and 0.341,respectively.Overall,the quality of Croci Stigma in Zhejiang province was the highest.Conclusion The established entropy weighted TOPSIS method is objective,comprehensive and effective,which can be used for the comprehensive quality evaluation of Croci Stigma.
作者
张梦奇
李彬
王琼芬
张红萍
石婧
徐虹
吴纤愫
ZHANG Mengqi;LI Bin;WANG Qiongfen;ZHANG Hongping;SHI Jing;XU Hong;WU Qiansu(Zhoushan Institute for Food and Drug Control,Zhejiang Province,Zhoushan 316000,China)
出处
《医药导报》
CAS
北大核心
2023年第12期1825-1830,共6页
Herald of Medicine
基金
浙江省基础公益研究计划项目(LGC21H280001)
浙江省市场监督管理局科研计划项目(ZC2021B094)。
关键词
西红花
熵权逼近理想解排序
质量评价
含量测定
波长切换
Croci Stigma
entropy weighted TOPSIS
quality evaluation
Content determination
wavelength switching