摘要
本文报道1例以腹水及双下肢水肿为首发表现,经超声心动图发现下腔静脉及右心房占位,结合甲胎蛋白明显升高、影像学检查临床诊断肝癌合并下腔静脉及右心房癌栓,应用靶向治疗联合免疫治疗后肿瘤有所缩小,甲胎蛋白明显降低,提示靶向治疗联合免疫治疗有效。本例患者中位生存时间3个月,有明确的乙肝肝硬化病史,临床诊断肝癌已经晚期,提示进行早期肝癌筛查的重要性。
One case with ascites and lower limb edema as the initial manifestations was reported.The echocardiography revealed inferior vena cava and right atrial occupation,which combined with increased alpha fetoprotein and imaging examination,suggested liver malignant tumor combined with tumor thrombus of inferior vena cava and right atrium.After targeted therapy combined with immunotherapy,the tumor shrank and alpha fetoprotein decreased significantly,suggesting that the treatment was effective.The median survival time of the patient was 3 months.This patient had a clear history of cirrhosis due to hepatitis B and was clinically diagnosed with advanced liver cancer,which suggested the importance of early liver cancer screening.
作者
张素巧
张咏梅
林洁
朱宇清
ZHANG Suqiao;ZHANG Yongmei;LIN Jie;ZHU Yuqing(International Medical Department of General Medicine,China-Japan Friendship Hospital,Beijing 100029,China;Department of Pathology,China-Japan Friendship Hospital,Beijing 100029,China)
出处
《中国医学科学院学报》
CAS
CSCD
北大核心
2023年第6期1011-1014,共4页
Acta Academiae Medicinae Sinicae
关键词
肝癌
下腔静脉癌栓
右心房癌栓
甲胎蛋白
liver cancer
inferior vena cava tumor thrombus
right atrial tumor thrombus
alpha fetoprotein