胸腔镜肺段切除术在治疗老年早期非小细胞肺癌患者中的临床效果及对肺功能、并发症的影响

Clinical Effect of Thoracoscopic Segmental Resection in the Treatment of Elderly Patients with Early Non-small Cell Lung Cancer and Its Influence on Lung Function and Complications

目的探讨胸腔镜肺段切除术治疗老年早期非小细胞肺癌的效果及对肺功能、并发症的影响。方法回顾性分析宁夏医科大学总医院2021年1月—2023年1月收治的81例老年早期非小细胞肺癌患者的病例资料,根据手术治疗方式分组,其中行胸腔镜肺叶切除术40例患者为参照组,行胸腔镜肺段切除的41例患者为研究组。对比两组手术相关指标、肺功能、并发症发生情况及生活质量。结果研究组手术时间长于参照组,术中出血少于参照组,住院时间短于参照组,差异有统计学意义(P<0.05);治疗1个月及治疗3个月后研究组第1秒用力呼气容积、用力肺活量指标均高于参照组,差异有统计学意义(P<0.05);两组并发症发生率差异无统计学意义(P>0.05);治疗后研究组生活质量评分为(112.34±6.31)分高于参照组的(98.67±5.46)分,差异有统计学意义(t=10.415,P<0.05)。结论对早期非小细胞肺癌实施胸腔镜肺段切除术更利于减少术中出血量、缩短术后康复进程及改善肺部功能,进而利于提高患者术后生活质量。

Objective To investigate the effect of thoracoscopic segmental resection in the treatment of senile nonsmall cell lung cancer(NSCLC)and its effects on lung function and complications.Methods 81 elderly patients with early NSCLC admitted to Ningxia Medical University General Hospital from January 2021 to January 2023 were retro⁃spectively selected and grouped according to surgical treatment.40 patients who underwent thoracoscopic lobectomy were the reference group,and 41 patients who underwent thoracoscopic segmental resection were the study group.Operation-related indexes,lung function,complications and quality of life were compared between the two groups.Results The operation time of the study group was longer than that of the reference group,the intraoperative bleeding was less than that of the reference group,and the hospital stay was shorter than that of the reference group,and the dif⁃ferences were statistically significant(P<0.05).Forced expiratory volume and forced vital capacity in the first second of the study group were higher than those of the reference group after 1 month and 3 months of treatment,and the dif⁃ferences were statistically significant(P<0.05).There was no significant difference in the incidence of complications between the two groups(P>0.05).After treatment,the quality of life scores of the study group[(112.34±6.31)points]were higher than that of the reference group[(98.67±5.46)points],and the differences were statistically significant(t=10.415,P<0.05).Conclusion Thoracoscopic segmental resection for early NSCLC is more conducive to reducing intra⁃operative blood loss,shortening postoperative rehabilitation process and improving lung function,and thus improving postoperative quality of life of patients.