高血压患者颈动脉搏动指数和阻力指数与动态心电血压监测指标的相关性研究

Correlation between carotid pulse index and resistance index with ambulatory electrocardiographic blood pressure monitoring indicators in patients with hypertension

目的 探讨高血压患者颈动脉搏动指数和阻力指数与动态心电血压监测指标的相关性。方法 回顾性分析2021年1月至2022年1月在该院诊治的800例原发性高血压患者,将其纳入研究组,同期300例健康体检者纳入对照组。监测并对比对照组和研究组的颈动脉搏动指数、阻力指数、24 h平均舒张压和收缩压、白昼和夜间平均舒张压和收缩压、24 h舒张压负荷和24 h收缩压负荷。将研究组患者按照搏动指数和阻力指数进行三分位分组,分析高血压患者颈动脉搏动指数和阻力指数与动态心电血压监测指标之间的相关性。结果 研究组颈动脉搏动指数、阻力指数、24 h平均舒张压、24 h平均收缩压、白昼平均舒张压、夜间平均舒张压、白昼平均收缩压、夜间平均收缩压、24 h舒张压负荷和24 h收缩压负荷均高于对照组,差异均有统计学意义(P<0.05)。随着颈动脉搏动指数的升高,高血压患者的24 h平均舒张压、24 h平均收缩压、白昼平均舒张压、白昼平均收缩压、24 h舒张压负荷、24 h收缩压负荷均明显升高,差异均有统计学意义(P<0.05);随着阻力指数的升高,高血压患者的24 h平均舒张压、24 h平均收缩压、白昼平均舒张压、夜间平均舒张压、白昼平均收缩压、夜间平均收缩压、24 h舒张压负荷和24 h收缩压负荷均明显升高,差异均有统计学意义(P<0.05)。相关性分析结果显示,高血压患者颈动脉搏动指数、阻力指数分别与24 h平均舒张压、24 h平均收缩压、白昼平均舒张压、白昼平均收缩压、24 h舒张压负荷和24 h收缩压负荷呈正相关性(r>0.3,P<0.001)。结论 高血压患者颈动脉搏动指数和阻力指数的变化与动态心电血压监测指标24 h平均血压、白昼平均血压、24 h血压负荷呈正相关,随着颈动脉搏动指数和阻力指数的升高,部分动态心电血压监测指标也相应升高。

Objective To investigate the correlation between the carotid pulse index and resistance index with ambulatory electrocardiographic blood pressure monitoring indicators in the patients with hypertension.Methods A retrospective analysis was conducted on 800 patients with essential hypertension diagnosed and treated in this hospital from January 2021 to January 2022.The patients were included in the study group.At the same time,300 healthy volunteers undergoing the physical examination were included in the control group.The carotid pulse index,resistance index,24 h average diastolic and systolic blood pressure,daytime and nighttime average diastolic and systolic blood pressure,24 h diastolic pressure load and 24 h systolic pressure load were monitored and compared between the control group and study group.The patients in the study group conducted the tertile grouping according to the pulse index and resistance index,and the correlation between the carotid pulse index and resistance index with ambulatory electrocardiographic blood pressure monitoring indicators in patients with hypertension was analyzed.Results The carotid pulse index,resistance index,24 h mean diastolic pressure,24 h mean systolic pressure,daytime mean diastolic pressure,nighttime mean diastolic pressure,daytime mean systolic pressure,nighttime mean systolic pressure,24 h diastolic pressure load and 24 h systolic pressure load in the study group were higher than those in the control group,and the differences were statistically significant(P<0.05);with the increase of carotid pulse index,the 24 h mean diastolic pressure,24 h mean systolic pressure,daytime mean diastolic pressure,daytime mean systolic pressure,24 h diastolic pressure load,24 h systolic pressure load in hypertensive patients were increased significantly,and the differences were statistically significant(P<0.05);With the increase of resistance index,the 24 h mean diastolic blood pressure,24 h mean systolic blood pressure,daytime mean diastolic blood pressure,nighttime mean diastolic blood pressure,daytime mean systolic blood pressure,nighttime mean systolic blood pressure,24 h diastolic blood pressure load and 24 h systolic blood pressure load in hypertensive patients were significantly increased,and the differences were statistically significant(P<0.05).The correlation analysis results showed that the carotid pulse index and the carotid resistance index was positively correlated with 24 h mean diastolic pressure,24 h mean systolic pressure,daytime mean diastolic pressure,daytime mean systolic pressure,24 h diastolic pressure load and 24 h systolic pressure load in hypertensive patients(r>0.3,P<0.001).Conclusion The changes of carotid pulse index and resistance index in hypertensive patients are positively correlated with the ambulatory electrocardiographic blood pressure monitoring indicators such as 24 h mean blood pressure,daytime mean blood pressure and 24 h blood pressure load.With the increase of carotid pulse index and resistance index,some ambulatory electrocardiographic blood pressure monitoring indicators are also increased correspondingly.