从“瘀毒”论治消渴肾病机制探析

Exploration on Mechanism in the Treatment of Wasting-Thirst Renal Diseasefrom the Perspective of “Stasis Toxin”

糖尿病肾脏疾病归属于中医“消渴肾病”范畴,是消渴日久不愈所并发的疑难病症。本文通过对“瘀毒”理论分析以及对消渴肾病的发病机制探讨,认为“瘀毒”与消渴肾病关系密切,“瘀毒损伤肾络”是消渴肾病发生发展的主要病机。基于此,本文提出了消渴肾病“解毒化瘀通络”的治疗原则,并根据消渴肾病“本虚标实”的病性,祛邪不忘扶正,攻补兼施,辨证施治。同时附验案一则以佐证,以期为消渴肾病的中医治疗提供一定的借鉴。

Diabetic kidney disease belongs to the category of wasting-thirst renal disease in traditional Chinese medicine(TCM),which is a difficult disease due to prolonged wasting-thirst.Based on the theoretical analysis of“stasis toxin”and the discussion of the pathogenesis of wasting-thirst renal disease,we believe that“stasis toxin”is closely related to wasting-thirst renal disease,and that“stasis toxin impairing kidney collaterals”is the main pathogenesis of the disease.Based on this theory and according to the nature of“deficiency in root and excess in branch”of the disease,we put forward the treatment principle for wasting-thirst disease of“detoxicating,resolving stasis and freeing the collateral vessels”.We should not forget to strengthen the body healthy qi while eliminating the pathogenic factors,and therefore,treatment should be performed according to syndrome differentiation.A case is attached to prove this correct treatment,so as to provide some reference for the treatment of wasting-thirst renal disease in traditional Chinese medicine.