摘要
Stroke is a significant leading cause of death and disability in the United States(Tsao et al.,2022).Approximately 87% of strokes fall into the ischemic category,mainly caused by arterial blockage(Jayaraj et al.,2019).Although the only FDA-approved effective medication is tissue plasminogen activator(tPA),it should be administrated within 4.5 hours of ischemic stroke.Furthermore,tPA has been an integral part of managing acute ischemic stro ke.
基金
supported by the UTHSC Bridge funding award (E073005058 Bridge Support-2022)
the National Institute of Health (R01-NS09 7800 and R56 NS127924-01) to TI。
