富硒酵母植物甾醇酯软胶囊辅助降血脂功能研究

Assist hypolipidemic effect of selenium yeast and phytosterol ester soft capsules

为研究富硒酵母植物甾醇酯软胶囊辅助降血脂的效果,开展人体试食试验。本研究有效受试者104例,试食组58例,对照组56例。试食组每日服用富硒酵母植物甾醇酯软胶囊,对照组服用安慰剂。连续服用60天,检测相关指标。试食组前后比较,血清总胆固醇、甘油三酯及低密度脂蛋白胆固醇有显著性差异(P<0.05),而高密度脂蛋白胆固醇无显著性差异(P>0.05)。试验后,两组受试者甘油三酯、总胆固醇、低密度脂蛋白胆固醇组间比较,均有显著性差异(P<0.05),而高密度脂蛋白胆固醇组间比较无显善性差异(P>0.05)。试验期间未见与受试品或安慰剂有关的不良反应,并且受试者的安全性检查指标均未见明显变化或异常现象。根据辅助降血脂功能评价方法判定标准,认为富硒酵母植物醇酯软胶囊具有辅助降血脂功能。

The human trial was carried out in order to study the assist hypolipidemic effect of selenium yeast and phytosterol ester soft capsules on hyperlipmia.There were 104 effective subjects in this research,58 cases in the trial group,56 cases in the control group.The trial group took selenium yeast and phytosterol ester soft capsules daily,and the control group took a placebo daily for 60 days and the related indicators were detected.There were significant differences in total serum cholesterol,triglyceride and low-density lipoprotein cholesterol contents(P<0.05)in the trial group,while there was no significant difference in HDL cholesterol contents(P>0.05).After the test,there were significant differences in triglycerides,total cholesterol,and LDL cholesterol contents between the two groups of subjects(P<0.05),but there was no significant difference in the HDL cholesterol contents(P>0.05).During the test there were no adverse reactions related to the test product or placebo,and there were no significant changes or abnormalities in the safety check indicators of the subjects.According to the criteria for the evaluation method of hypolipidemic function,it is believed that selenium yeast and phytosterol ester soft capsules have the function of reducing blood lipid.