(E)-4-(3,5-二溴-4-羟基苯亚甲基氨基)-2,3-二甲基-1-苯基-1,2-二氢吡唑-5-酮的合成与表征

The Synthesis and Characterization of(E)-4-(3,5-Dibromo-4-Hydroxyphenylmethylene Amino)-2,3-Dimethyl-1-Phenyl-1,2-Dihydropyrazole-5-One

采用3,5-二溴-4-羟基苯乙醛与4-氨基安替比林以甲醇作为溶剂通过缩合反应合成了(E)-4-(3,5-二溴-4-羟基苯亚甲基氨基)-2,3-二甲基-1-苯基-1,2-二氢吡唑-5-酮。对所生成化合物采用乙醇进行结晶,5 d后获得浅黄色的晶体,其结构经X-射线单晶衍射表征,属单斜晶系,P21/c空间群,晶胞参数a=12.0197(11),b=10.8239(10),c=13.3921(12),β=94.870(2)°,V=1736.0(3)3,Z=4,D x=1.780 mg·m-3,θ=2.4~25.5°,μ=4.69 mm-1,T=295(2)K,利用傅里叶变换红外光谱仪得到产物的红外光谱图。

In this paper(E)-4-(3,5-dibromo-4-hydroxyphenylimino)-2,3-dimethyl-1-phenyl-1,2-dihydropyrazole-5-one was synthesized by condensation reaction using 3,5-dibromo-4-hydroxyphenylacetaldehyde and 4-aminoantipyrine in methanol as solvent.The generated compound was crystallized using ethanol,and after 5 days,a light yellow crystal was obtained.Its structure was characterized by X-ray single crystal diffraction,belonging to the monoclinic system,P21/c space group,cell parameters a=12.0197(11),b=10.8239(10),c=13.3921(12),β=94.870(2)°,V=1736.0(3)3,Z=4,D x=1.780 mg·m-3,θ=2.4-25.5°,μ=4.69 mm-1,T=295(2)K.Obtain the infrared spectrum of the product using a Fourier transform infrared spectrometer.