动物源性食品中酰胺醇类药物残留检测研究进展

Research progress in the detection of amide alcohol drugsin animal-origin foods

酰胺醇类药物半衰期较长,进入人体后难以通过自身代谢排出体外,过量的酰胺醇类药物残留会对人体器官造成严重的危害,因此中国制定了酰胺醇类药物最高残留限量标准,其中氯霉素在所有可食组织中均不得检出。文章综述了动物源性食品中常见的酰胺醇类药物残留检测方法,包括色谱法、质谱法、电化学法与电致化学发光法、免疫法、荧光法和表面增强拉曼光谱法等,分析了这些方法的优缺点,并对今后酰胺醇类药物残留检测的新技术进行了展望。

Amide alcohol drugs have a long half-life and are difficult to excrete through the metabolic process after entering the human body.Excessive amide alcohol drugs will cause serious harm to human organs.Therefore,China has formulated a strict maximum residue limit standard for amide alcohol drugs,in which chloramphenicol can’t be detected in all edible tissues.This review introduces the application of chromatography,mass spectrometry,electrochemical method,electrochemiluminescence method,immunoassay,fluorescence method and surface-enhanced Raman spectroscopy method in the detection of amide alcohol drugs in animal-origin foods,and the advantages and disadvantages of these methods are analyzed and new techniques for the detection of amidol alcohol drugs in the future are prospected.