可吸收止血绒S-100在骨折内固定手术患者中的应用效果

Application Effect of Absorbable Hemostatic Velvet S-100 in Patients Undergoing Fracture Internal Fixation Surgery

目的:分析可吸收止血绒S-100在骨折内固定手术患者中的应用效果。方法:回顾性选取2022年3月—2023年6月河南省胸科医院收治的106例骨折内固定手术患者作为研究对象。根据可吸收止血绒S-100的使用情况将其分为对照组和观察组,各53例。对照组术中采用气囊止血带止血,观察组术中采用可吸收止血绒S-100。比较两组围手术期指标,引流量及引流管拔管时间,术前及术后第3天凝血功能。结果:观察组手术时间及住院时间均短于对照组,术中出血量少于对照组,差异有统计学意义(P<0.05)。观察组术后24 h、48 h引流量少于对照组,引流管拔管时间短于对照组,差异有统计学意义(P<0.05)。术后第3天,两组凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)均降低,纤维蛋白原(FIB)及D-二聚体(D-D)均明显升高,观察组PT及APTT均高于对照组,FIB及D-D均低于对照组,差异有统计学意义(P<0.05)。结论:可吸收止血绒S-100应用在骨折内固定手术中止血效果显著,能减少局部渗出,缩短引流周期,对患者凝血功能影响较小。

Objective:To analyze the application effect of absorbable hemostatic velvet s-100 in patients undergoing fracture internal fixation surgery.Method:A total of 106 patients with fracture internal fixation surgery admitted to Henan Chest Hospital from March 2022 to June 2023 were retrospectively selected as the study objects.According to the use of absorbable hemostatic velvet S-100,they were divided into control group and observation group,53 cases in each group.The control group was treated with balloon tourniquet for hemostasis in intraoperative,the observation group was treated with absorbable hemostatic velvet S-100 for hemostasis in intraoperative.Perioperative indexes,volume of drainage,drainage tube extubation time,and coagulation function before and on the 3rd day after surgery were compared between the two groups.Result:The surgery time and hospital stay in the observation group were shorter than those in the control group,and the amount of intraoperative blood loss was less than that in the control group,the differences were statistically significant(P<0.05).The drainage volume in the observation group was lower than that in the control group at 24 h and 48 h after surgery,and the drainage tube decannulation time was shorter than that in the control group,the differences were statistically significant(P<0.05).On the 3rd day after surgery,prothrombin time(PT)and activated partial thromboplastin time(APTT)were decreased in both groups,while fibrinogen(FIB)and D-dimer(D-D)were significantly increased in both groups,PT and APTT in observation group were higher than those in control group,and FIB and D-D were lower than those in control group,the differences were statistically significant(P<0.05).Conclusion:The application of absorbable hemostatic velvet S-100 in fracture internal fixation surgery has remarkable hemostatic effect,can reduce local exudation,shorten the drainage cycle,and has little influence on the coagulation function of patients.