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Bioelectronic medicine in modulation of cortical spreading depolarization and beyond

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摘要 Bioelectronic interventions,specifically trigeminal nerve st imulat ion(TNS),have attracted considerable attention in conditions where cortical spreading depolarizations(CSDs)accompanied by compromised cerebral perfusion may exacerbate neurological damage.While pharmacological interventions have demonstrated initial potential in addressing CSDs,a standardized treatment approach has not yet been established.The objective of this perspective is to explore emerging bioelectronic methodologies for addressing CSDs,particularly emphasizing TNS,and to underscore TNS’s capacity to enhance neurovascular coupling and cerebral perfusion.
出处 《Neural Regeneration Research》 SCIE CAS 2025年第2期481-482,共2页 中国神经再生研究(英文版)
基金 supported by National Institute of Neurological Disorders and Stroke of the National Institutes of Health under award number R21NS114763 US Army Medical Research and Materiel Command (USAMRMC) under award#W81XWH-18-1-0773 merit-based career enhancement award at the Feinstein Institutes for Medical Research (to CL)
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