摘要
抗MDA5抗体阳性临床无肌病性皮肌炎是一种特殊类型皮肌炎,间质性肺病是其主要肺部并发症,国内少见,本文报道一例并做文献分析。患者,女,67岁。面颈部、肩背部及双手等多处红斑,伴四肢酸痛无力50天。肌炎抗体谱示:抗MDA5抗体IgG(+++),抗SRP抗体IgG(+),抗SSA/Ro-52抗体(+)。胸部CT提示双肺间质纤维化伴感染。结合组织病理学检查,诊断为临床无肌病性皮肌炎(抗MDA5抗体阳性)。
Clinical amyopathic dermatomyositis with anti-MDA5 antibody positive is a special type of dermatomyositis.Interstitial lung disease is the main pulmonary complication of this disease,which is rare in China.We reports a case of clinical amyopathic dermatomyositis with anti-MDA5 antibody positive and reviews the literature.A 67-year-old female presented with multiple erythematous plaques on the face and neck,back of the shoulders and hands,with aching and weakness of the limbs for 50 days.Myositis antibody spectrum showed anti-MDA5 antibody IgG(++++),anti-SRP antibody IgG(+),anti-SSA/Ro-52 antibody(+).Chest CT revealed bilateral interstitial lung fibrosis with infection.The diagnosis of clinical amyopathic dermatomyositis(anti-MDA5 antibody-positive) was made.
作者
米倩
孟昭影
杨金良
MI Qian;MENG Zhaoying;YANG Jinliang(Graduate School of Hebei North University,Zhangjiakou 075000,China;The First Affiliated Hospital of Hebei North University,Zhangjiakou 075000,China)
出处
《中国麻风皮肤病杂志》
2024年第7期494-498,共5页
China Journal of Leprosy and Skin Diseases
