睾丸扭转患者以睾丸切除为结局的危险因素分析

Risk factors analysis of testicular torsion patients with testicular resection as the outcome

目的探讨睾丸扭转患者以睾丸切除为结局的危险因素,以期为该病的临床防治提供思路。方法回顾性分析2012年1月1日—2023年3月1日在广东医科大学附属医院就诊的117例睾丸扭转患者的临床资料,其中43例行睾丸复位固定术,74例行睾丸切除术。通过单因素分析患者术前炎性、凝血相关指标、睾丸扭转角度及缺血和疑似扭转睾丸检查(TWIST)评分等指标与治疗术式的相关性,通过二元logistic回归分析睾丸扭转患者以睾丸切除为结局的独立危险因素,通过受试者工作特征(ROC)曲线判断各因素对睾丸扭转术式的预测价值。结果二元logistic回归分析显示:发病时间长(OR=1.841,P=0.036)、扭转角度大(OR=1.005,P=0.016)、TWIST评分高(OR=2.225,P=0.003)和纤维蛋白原(FIB)水平升高(OR=2.489,P=0.049)是睾丸扭转患者以睾丸切除为结局的独立危险因素。ROC曲线分析显示上述4个因素的最佳截断点分别为1.75 d、225°、3.5分和3.155 g/L,ROC曲线下面积(AUC)分别为0.893、0.718、0.812和0.770。结论发病时长、扭转角度、TWIST评分和FIB水平是睾丸扭转患者以睾丸切除为结局的独立影响因素,具有一定的预测价值。

Objective To explore the risk factors that affect the outcome of testicular torsion in patients with testicular resection,to provide ideas for clinical management.Methods The clinical data of 117 patients with testicular torsion treated in our hospital during Jan.1,2012 and Mar.1,2023 were retrospectively analyzed,43 of whom underwent testicular detorsion and orchidopexy,and 74 underwent orchiectomy.The correlation between preoperative inflammatory and coagulation-related indicators,testicular torsion angle,TWIST score and orchiectomy was analyzed with univariate analysis.The independent risk factors for testicular torsion patients with testicular resection as the outcome were analyzed with binary logistic regression.The predictive value of each factor for orchiectomy was assessed with receiver operating characteristic(ROC)curve.Results Binary logistic regression analysis indicated that long duration of onset(OR=1.841,P=0.036),large torsion angle(OR=1.005,P=0.016),high TWIST score(OR=2.225,P=0.003)and elevated FIB level(OR=2.489,P=0.049)were independent risk factors for testicular torsion patients with testicular resection as the outcome.ROC curve analysis showed that the best cut-off value of the above 4 factors to predict orchiectomy were 1.75 days,225°,3.5 and 3.155 g/L;the area under the ROC curve(AUC)were 0.893,0.718,0.812 and 0.770,respectively.Conclusion The duration of onset,torsion angle,TWIST score,and FIB level are independent risk factors for testicular torsion patients with testicular resection as the outcome,and these indicators have certain predictive value.