远隔缺血预适应治疗对急性缺血性卒中脑血管狭窄患者颅内血管狭窄程度及血清指标的影响

Effect of Remote Ischemic Preconditioning on Intracranial Vascular Steno⁃sis Degree and Serum Indexes in Patients with Acute Ischemic Stroke

目的 探讨急性缺血性卒中(Acute Ischemic Stroke, AIS)脑血管狭窄患者采用远隔缺血预适应(Remote Ischemic Preconditioning, RIPC)治疗对颅内血管狭窄程度及血清指标的影响。方法 随机选取聊城市第三人民医院于2021年5月—2023年7月收治的80例AIS脑血管狭窄患者为研究对象,以随机数表法分成对照组(n=40)和研究组(n=40),对照组给予常规对症治疗,研究组给予RIPC治疗,比较两组颅内血管狭窄程度、神经功能、血清指标、日常生活能力。结果 治疗后,研究组颅内血管直径狭窄程度(18.23±3.46)%较对照组(27.85±4.19)%更低,差异有统计学意义(t=11.197,P<0.05);研究组颅内血管面积狭窄程度(17.64±4.03)%较对照组(26.79±5.02)%更低,差异有统计学意义(t=8.989,P<0.05);研究组神经功能评分和各项血清指标均低于对照组,差异有统计学意义(P均<0.05);研究组日常生活能力评分高于对照组,差异有统计学意义(P<0.05)。结论 RIPC应用于AIS脑血管狭窄患者治疗中,能够降低颅内血管狭窄程度,改善神经功能、血清指标,提高日常生活能力。

Objective To investigate the effect of remote ischemic preconditioning(RIPC)on the degree of intracranial vascular stenosis and serum indexes in patients with acute ischemic stroke(AIS).Methods A total of 80 AIS cerebro-vascular stenosis patients admitted to the Liaocheng Third People's Hospital from May 2021 to July 2023 were ran-domly selected as the research objects.They were divided into control group(n=40)and study group(n=40)by random number table method.The control group was given routine symptomatic treatment,and the study group was given RIPC treatment.The degree of intracranial vascular stenosis,neurological function,serum index and daily living abil-ity were compared between the two groups.Results After treatment,the degree of intracranial vascular diameter steno-sis in the study group(18.23±3.46)%was lower than that in the control group(27.85±4.19)%,and the difference was statistically significant(t=11.197,P<0.05);the degree of stenosis of intracranial vascular area in the study group(17.64±4.03)%was lower than that in the control group(26.79±5.02)%,and the difference was statistically signifi-cant(t=8.989,P<0.05);the neurological function score and serum indexes of the study group were lower than those of the control group,and the differences were statistically significant(all P<0.05);the daily living ability score of the study group was higher than that of the control group,and the difference was statistically significant(P<0.05).Conclu-sion The application of RIPC in the treatment of AIS cerebrovascular stenosis can reduce the degree of intracranial vascular stenosis,improve neurological function and serum indexes,and improve the ability of daily living.