药物重整与药学服务模式用于心血管内科效果分析

Application Effect of Medication Reconciliation and Pharmaceutical Care Mode in Cardiovascular Medicine

目的 探讨药物重整与药学服务模式用于心血管内科的效果。方法 参考《医疗机构药学服务规范》(第3部分药物重整)及澳大利亚药学会综合药物管理评价指南,建立心血管内科的药物重整与药学服务模式。选取医院心血管内科2019年3月至2021年3月(模式实施前)收治的340例心血管疾病患者为对照组,采用常规药学服务模式;以2021年4月至2022年4月(模式实施后)收治的340例心血管疾病患者为观察组,采用药物重整与药学服务模式,比较两组患者用药不一致、不合理用药、药品不良反应(ADR)的发生情况及药品相关费用。结果 观察组患者药物用法用量改变、品种更换、厂家更换、种类增加比例均显著低于对照组,用药途径不合理、联合用药不合理、药物剂量过大、严重ADR的发生率均显著低于对照组,观察组患者的住院药品费用、住院总费用及出院1个月药品费用均显著少于对照组(P <0.05)。结论 药物重整与药学服务模式用于心血管内科,能显著减少心血管疾病患者的治疗费用,并有效提高用药安全性。

Objective To investigate the application effect of medication reconciliation and pharmaceutical care mode in cardiovascular medicine.Methods Based on the Part 3(Medication Reconciliation)of the Regulations for Pharmaceutical Care in Medical Institutions and the Comprehensive Medication Management Review,a medication reconciliation and pharmaceutical care mode in cardiovascular medicine was established.A total of 340 patients with cardiovascular disease admitted to the cardiovascular medicine of the hospital from March 2019 to March 2021(before the implementation of the mode)were selected as the control group,and they were given the routine pharmaceutical care mode.Another 340 patients with cardiovascular disease admitted to the hospital from April 2021 to April 2022(after the implementation of the mode)were selected as the observation group,and they were given the medication reconciliation and pharmaceutical care mode.The incidences of medication inconsistency,irrational drug use,adverse drug reactions(ADRs)and relevant drug costs between the two groups were compared.Results The proportions of changes in drug usage,dosage,variety,manufacturer and increase in variety in the observation group were significantly lower than those in the control group;the incidences of irrational medication routes,irrational drug combination,overdosage and serious ADRs in the observation group were significantly lower than those in the control group;the drug costs during hospitalization,total costs during hospitalization and drug costs after one month of discharge in the observation group were significantly less than those in the control group(P<0.05).Conclusion The application of medication reconciliation and pharmaceutical care mode in cardiovascular medicine can significantly decrease the treatment costs for patients with cardiovascular disease and effectively improve the medication safety.