广州市某三甲医院人类免疫缺陷病毒感染者用药安全行为风险的“知信行”调查及分析

KAP Survey on Medication Among AIDS Patients in a 3 A-grade Hospital of Guangzhou

【目的】了解广州市某三甲医院人类免疫缺陷病毒(HIV)感染者用药安全行为风险的知识掌握情况及相关态度和行为,为艾滋病防治提供科学依据。【方法】以我院就诊的18岁及以上的HIV感染者作为调查对象,采用问卷调查的形式,调查其艾滋病用药安全行为风险的知识、态度、行为情况。【结果】共回收问卷549份,有效问卷503份,有效率为91.6%。503名调查对象艾滋病用药安全行为风险的平均知识评分、态度评分、行为评分为(14.58±8.49)分、(25.21±6.92)分、(47.58±3.33)分;知识、态度、行为得分率分别为36.46%、63.02%、95.16%。不同年龄、教育程度、职业人群的知识评分比较,差异均有统计学意义(P<0.05)。多重线性回归显示教育程度、医保状态对知识评分影响显著(P<0.05);不同教育程度人群的态度评分比较,差异均有统计学意义(P<0.05);不同职业人行为评分比较,差异均有统计学意义(P<0.05);多重线性回归显示年龄、职业、知识得分和态度得分对行为评分影响显著(P<0.05);患者期望获得药师的药学服务,主要形式包括面对面沟通、网络平台咨询和电话咨询。用药知识需求包括药物不良反应知识及应对措施、避免药物相互作用,和漏服药的应对办法并提高依从性的措施。【结论】广州市某三甲医院HIV感染者对艾滋病用药安全行为风险的合理用药意识良好,但用药知识掌握情况有待提高,个别不良习惯,可能会影响服药依从性,导致用药安全隐患。患者对开展艾滋病合理用药相关药学服务的需求迫切。

【Objective】To evaluate the knowledge,attitude and practice(KAP)of medication use and safety among the patients with acquired immune deficiency syndrome(AIDS)in a 3A-grade hospital of Guangzhou city,and to provide scientific basis for AIDS prevention and treatment.【Methods】A questionnaire survey was conducted among AIDS patients aged 18 years and above in our hospital to investigate their KAP regarding medication use and safety.【Results】A total of 549 questionnaires were collected,of which 503 were valid,with an effective recovery rate of 91.6%.The average scores of KAP were(14.58±8.49),(25.21±6.92)and(47.58±3.33),respectively,with the scoring rates of 36.46%,63.02%,and 95.16%,respectively.There were statistically significant differences(P<0.05)in knowledge scores among people with different ages,education levels and occupations.Multiple linear regression showed that education level and medical insurance status had most significant impact on knowledge scores(P<0.05).Significant differences were found in attitude scores among people with different education levels(P<0.05),as well as in practice scores among people with different occupations(P<0.05).Multiple linear regression revealed that age,occupation,knowledge score and attitude score had a significant impact on practice scores(P<0.05).Patients expected to receive pharmaceutical care services from the pharmacists via face-to-face communication,network platform and telephone consultation on medication knowledge such as adverse drug reactions and response measures,drug-drug interactions,missed medication and response measures,medication adherence measures,etc.【Conclusions】AIDS patients in this hospital have a good awareness of medication safety,but their knowledge of medication use needs improvement.Some bad habits may affect their compliance,resulting in safety hazards.Therefore,there is an urgent demand for pharmaceutical care services related to rational drug use.