T1 mapping技术及在评估心肌纤维化中的应用进展

Progress of T1 Mapping and Its Application in Evaluating Myocardial Fibrosis

T1 mapping技术是近年来应用较为广泛的MRI新技术,其通过量化心肌组织的T1值和细胞外容积分数,可对导致心肌纤维化的疾病进行评估。本文综述T1 mapping的基本原理、扫描序列及在导致心肌纤维化的疾病中的应用,主要包括心梗、肥厚型心肌病、扩张型心肌病、先天性心脏病、主动脉狭窄、高血压性心脏病、糖尿病心肌病、尿毒症性心肌病、射血分数保留型心衰、心脏移植等。

T1 mapping is a widely-used magnetic resonance technology in recent years. By quantifying the T1 value and extracellular volume of myocardial tissue, T1 mapping can evaluate the cardiovascular diseases leading to myocardial fibrosis. The basic principle,scanning sequence and application of T1 mapping are reviewed in diseases leading to myocardial fibrosis, mainly including: myocardial infarction, hypertrophic cardiomyopathy, dilated cardiomyopathy, congenital heart disease, aortic stenosis, hypertensive heart disease,diabetic cardiomyopathy, uremic cardiomyopathy, heart failure with preserved ejection fraction, heart transplantation, etc.