温控相转移催化新体系中α,β-不饱和酮的常压加氢反应

Thermoregulated Phase-Transfer Catalysis System for Hydrogenation ofα,β-Unsaturated Ketones at Atmospheric Pressure

构建了一种由水、1-己醇和Ru纳米(Ru_(nano))催化剂组成的温控相转移(TPT)催化新体系,并将上述催化体系应用于查耳酮常压下的选择性加氢反应中。在优化后的反应条件下,查耳酮的转化率以及查耳酮中C==C双键加氢产物二氢查耳酮的选择性均高于99%,Ru_(nano)催化剂可重复使用6次,查耳酮的转化率和二氢查耳酮的选择性均保持不变。反应的转化频率(TOF)高于迄今所报道的常压H2下Ru_(nano)催化剂的最高值,且Ru的流失也得以进一步减少。此外,上述TPT催化新体系在其它α,β-不饱和酮的常压加氢反应中亦获得了高于99%的转化率和选择性。

A novel thermoregulated phase-transfer(TPT)catalysis system composed of H_(2)O,1-hexanol and Ru nanocatalyst(Ru_(nano) catalyst)was developed and utilized for the selective hydrogenation of chalcone at atmospheric H2 pressure.Under the optimal circumstances,both the conversion of chalcone and the selectivity for the product of C==C double bond hydrogenation from chalcone were above 99%.The Ru_(nano) catalyst is conveniently separable from product and directly recycled six times with conversion and selectivity remaining unchanged.The turnover frequency(TOF)was higher than that of previously reported Ru_(nano) catalyst and the leaching of Ru was further reduced.In addition,this novel TPT catalysis system was also extended to the atmospheric hydrogenation of otherα,β-unsaturated ketones with>99% conversion and selectivity.