常用血生化指标变化在高龄孕产妇围生期的临床意义

Clinical Significance of Changes in Commonly Used Blood Biochemical Index for Elderly Pregnant and Postpartum Women during Perinatal Period

目的探究常用血生化指标变化在高龄孕产妇围生期的临床意义。方法选择2021年1月—2022年12月本院收治的1000例高龄孕产妇设为观察组,适龄孕产妇1000例为对照组,均实施围生期血液学检验。比较分析凝血指标检测结果、血脂指标检测结果、妊娠并发症、妊娠合并症、围生儿结局等。结果观察组APTT、TT、PT低于对照组,FIB高于对照组(P<0.05)。两组D-二聚体(D-D)水平对比,差异无统计学意义(P>0.05)。观察组LDL-C、TC、TG低于对照组,HDL-C高于对照组(P<0.05)。观察组妊娠并发症高于对照组120例,差异有统计学意义(P<0.05)。观察组子宫肌瘤、心脏病、糖尿病的发生例数均高于对照组,差异有统计学意义(P<0.05)。观察组死亡、窒息总发生率高于对照组,差异有统计学意义(P<0.05)。结论高龄孕产妇,凝血、血脂等指标出现明显改变,母婴结局受到较大影响,提升妊娠期不良事件出现的风险,因此临床应定期做好对高龄孕产妇血脂等监测,以便能够改善妊娠结局。

Objective To explore clinical significance of changes in commonly used blood biochemical index for elderly pregnant and postpartum women during perinatal period.Methods The paper chose 1000 elderly pregnant women from January 2021 to December 2022 as observation group,and 1000 eligible pregnant women as control group,treated with perinatal hematological tests.R esults of coagulation and blood lipid indicators,pregnancy complications,pregnancy complications,and perinatal outcomes were compared and analyzed.Results APTT,TT,PT levles in observation group were lower than control group,and FIB was higher(P<0.05).There was no statistically significant difference in D-dimer(D-D)levels between two groups(P>0.05).LDL-C,TC,and TG levles in observation group were lower than control group,while HDL-C was higher(P<0.05).Observation group had 120 cases of pregnancy complications,higher than control group,difference was statistically significant(P<0.05).Number of cases of hysteromyoma,heart disease and diabetes in observation group was significantly higher than control group(P<0.05).Total incidence of death and asphyxia in observation group was higher than control group,difference was statistically significant(P<0.05).Conclusion There are significant changes in coagulation,blood lipids,and other indicators for elderly pregnant and postpartum women,with significant effect on maternal and infant outcomes,which can increase risks of adverse events during pregnancy.Therefore,regular monitoring of blood lipids should be taken for elderly pregnant and postpartum women in clinical practice to improve pregnancy outcomes.