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颅骨成形术后并发早期癫痫的危险因素

Risk factors for concurrent early epilepsy after cranioplasty
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摘要 目的探讨颅骨成形术后早期癫痫的危险因素。方法回顾性分析2015年1月至2021年12月收治的88例颅骨缺损病人的临床资料。采用塑形钛网进行颅骨成形术,术后7 d内发生癫痫发作诊断为术后早期癫痫,采取多因素logistic回归模型分析术后早期癫痫的危险因素。结果88例中,12例颅骨成形术后7 d内出现癫痫发作;术后早期癫痫发作的发生率为13.64%。多因素logistic回归分析显示,术后术区出血或积液为颅骨成形术后早期癫痫的独立危险因素(OR=8.394;95%CI 1.421~49.583;P=0.019)。结论术后早期癫痫是颅骨成形术后一种常见的并发症。采取有效措施防止术区出血或积液有助于降低颅骨成形术后早期癫痫的发生率。 Objective To explore the risk factors for early epilepsy after cranioplasty.Methods The clinical data of 88 patients with skull defects admitted from January 2015 to December 2021 were retrospectively analyzed.Cranioplasty was conducted using shaped titanium mesh,and epileptic seizures that occurred within 7 days after the operation were diagnosed as early postoperative epilepsy.A multivariate logistic regression model was adopted to analyze the risk factors for early postoperative epilepsy.Results Of the 88 cases,12 cases had epileptic seizures within 7 days after cranioplasty;the incidence of early postoperative epilepsy was 13.64%.Multivariate logistic regression analysis showed that postoperative hemorrhage or effusion in the operation area was an independent risk factor for early epilepsy after cranioplasty(OR=8.394;95%CI 1.421~49.583;P=0.019).Conclusions Early postoperative epilepsy is a common complication after cranioplasty.Taking effective measures to prevent hemorrhage or effusion in the operation area is helpful to reduce the incidence of early epilepsy after cranioplasty.
作者 刘晓亮 李威威 郎立峰 杨树成 丛大伟 田风富 LIU Xiao-liang;LI Wei-wei;LANG Li-feng;YANG Shu-cheng;Cong Da-wei;TIAN Feng-fu(Department of Neurosurgery,Yantai Affiliated Hospital of Binzhou Medical University,Yantai 264100,China)
出处 《中国临床神经外科杂志》 2024年第8期465-468,共4页 Chinese Journal of Clinical Neurosurgery
基金 烟台市科技创新发展计划(2022YD084) 滨州医学院科技计划项目(BY2020KJ53)。
关键词 颅骨成形术 术后早期癫痫 危险因素 Cranioplasty Early epilepsy Risk factors
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