聚类在流行病学分层分析中的应用

Cluster analysis applied in the epidemiological stratification analysis

目的 建立一种方法 ,解决当混杂因素分层界限不清或存在矛盾时 ,如何进行流行病学分层分析的问题。方法 采用SPSS 1 0 .0软件 ,以广东省 1 997～ 1 998年糖尿病流行病学调查资料为实例 ,进行聚类分层分析。结果 聚类分层分析提高了分层分析效率 ,有效地控制了混杂偏倚 ,避免了错分偏倚的产生。结论 聚类分析可以作为一种辅助分层的方法 ,合理解决当混杂因素分层界限不清或存在矛盾时 ,如何进行分层分析的问题。

Objective To establish a new method on stratification analysis when the stratification limits of confounding factors was not clear or contradictory. Method Data on a study of diabetes mellitus in Guangdong province collected in the year of 1997 and 1998 was analyzed using cluster stratification analysis. Results The efficiency of stratification analysis was improved and the confounding bias was effectively controlled with information bias avoided when the clusters stratification analysis was applied. Conclusion The problem was logically solved using cluster analysis as an assistant stratification means.